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意大利南部普利亚地区绝经后妇女的代谢综合征及其组成成分

Metabolic syndrome and its components in postmenopausal women living in southern Italy, Apulia region.

作者信息

Maiello Maria, Zito Annapaola, Ciccone Marco Matteo, Palmiero Pasquale

机构信息

ASL Brindisi, Cardiology Equipe, District of Brindisi, Italy.

Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Italy.

出版信息

Diabetes Metab Syndr. 2017 Jan-Mar;11(1):43-46. doi: 10.1016/j.dsx.2016.08.003. Epub 2016 Aug 22.

Abstract

OBJECTIVES

The goal of our study was to determine the prevalence of metabolic syndrome (MetS) and all its components, in a population of postmenopausal women aged over 45 years, consecutively accessed to our Heart Station, during 2014, for their first cardiac examination,furthermore to estimate their cardiovascular risk and the achievement of target blood values of main risk factors, according to current Guidelines.

METHODS

We screened 1257 postmenopausal women. MetS was assessed according to the National-Cholesterol-Education-Program-Adult-Treatment-Panel III definition. Cardiovascular risk was calculated by the Systematic Coronary Risk Evaluation (<65 years).

RESULTS

MetS was assessed on 834 women (66.4%). Prevalence of each component was: hypertension on 767 women (91.9%), central obesity 758 women (90.9%), low high-density lipoproteins cholesterol (HDLc) increased levels 612 women (73.3%), high triglyceride levels 428 women (51.3%), glucose levels higher than 110mg/dl or diabetes 404 women (48.5%). Cardiovascular risk was moderate until 65 years, but it increases after. Metabolic control in postmenopausal women was poor for glucose, only 82 women (9.8%) presented glucose levels lower than 110mg/dl, it was better for systolic blood pressure, that was normal in 564 women (67.6%) and worse for lipid levels.

CONCLUSION

The prevalence of metabolic syndrome in our population of postmenopausal women is high. Hypertension and central obesity are the more common components. The cardiovascular risk is moderate-high, the achievement of target values for glycemic and lipid levels is unsatisfactory, while systolic blood pressure is enough well controlled but however it is mandatory to improve this goal. An early MetS diagnosis and an early educational intervention are useful to decrease cardiovascular risk of postmenopausal women affected by metabolic syndrome.

摘要

目的

我们研究的目的是确定2014年连续到我们心脏科进行首次心脏检查的45岁以上绝经后女性人群中代谢综合征(MetS)及其所有组分的患病率,此外,根据当前指南评估她们的心血管风险以及主要危险因素的目标血值达标情况。

方法

我们筛查了1257名绝经后女性。根据美国国家胆固醇教育计划成人治疗小组第三次报告(NCEP-ATP III)的定义评估代谢综合征。通过系统性冠状动脉风险评估(<65岁)计算心血管风险。

结果

对834名女性(66.4%)进行了代谢综合征评估。各组分的患病率分别为:高血压767名女性(91.9%),中心性肥胖758名女性(90.9%),高密度脂蛋白胆固醇(HDLc)水平降低612名女性(73.3%),高甘油三酯水平428名女性(51.3%),血糖水平高于110mg/dl或糖尿病404名女性(48.5%)。65岁之前心血管风险为中度,但之后会增加。绝经后女性的代谢控制在血糖方面较差,只有82名女性(9.8%)血糖水平低于110mg/dl,收缩压方面较好,564名女性(67.6%)收缩压正常,血脂水平方面较差。

结论

我们的绝经后女性人群中代谢综合征的患病率很高。高血压和中心性肥胖是较常见的组分。心血管风险为中度偏高,血糖和血脂水平的目标值达标情况不理想,而收缩压控制得较好,但仍需改善这一目标。早期诊断代谢综合征并进行早期教育干预有助于降低受代谢综合征影响的绝经后女性的心血管风险。

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