Pingali Hema V, Hilliker Angela K
Department of Biology, University of Richmond, Richmond, VA 23173.
Department of Biology, University of Richmond, Richmond, VA 23173
J Cell Biol. 2016 Sep 12;214(6):649-52. doi: 10.1083/jcb.201608075. Epub 2016 Sep 5.
Translation is carefully regulated to control protein levels and allow quick responses to changes in the environment. Certain questions about translation in vivo have been unattainable until now. In this issue, Pichon et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201605024) describe a new technique to allow real-time monitoring of translation on single mRNAs.
翻译过程受到严格调控,以控制蛋白质水平并允许对环境变化做出快速反应。直到现在,一些关于体内翻译的问题仍无法解决。在本期中,皮雄等人(2016年。《细胞生物学杂志》http://dx.doi.org/10.1083/jcb.201605024)描述了一种新技术,可对单个mRNA上的翻译进行实时监测。