Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.
J Cell Biol. 2012 Apr 2;197(1):7-9. doi: 10.1083/jcb.201202140.
Although the physical separation of transcription in the nucleus and translation in the cytoplasm has presided as a fundamental tenet of cell biology for decades, it has not done so without recurring challenges and contentious debate. In this issue, David et al. (2012. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201112145) rekindle the controversy by providing convincing experimental evidence for nuclear translation.
尽管核内转录和细胞质内翻译的物理分离几十年来一直是细胞生物学的一个基本准则，但它并非没有反复出现的挑战和争议性辩论。在本期中，David 等人（2012. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201112145）提供了令人信服的实验证据，重新引发了关于核内翻译的争议。
