Gunes Alime, Yıldırım Bas Funda, Arslan Bahriye, Tok Levent, Tok Özlem, Salman Zeliha
a Department of Ophthalmology , Süleyman Demirel University Faculty of Medicine , Isparta , Turkey.
b Department of Family Medicine , Süleyman Demirel University Faculty of Medicine , Isparta , Turkey.
Semin Ophthalmol. 2018;33(2):175-178. doi: 10.1080/08820538.2016.1188127. Epub 2016 Sep 6.
To assess corneal parameters in constitutional thinness (CT) subjects and to compare them with those of healthy individuals.
Twenty-four CT subjects (BMI < 18.5 kg/m) and 24 healthy subjects (BMI: 18.5-25 kg/m2) were enrolled in this observational cross-sectional study. All participants were screened for age, gender, and medical history, then underwent a detailed ophthalmological examination. Corneal parameters were evaluated by Scheimpflug imaging. Height and weight of all subjects were measured and body mass index (BMI) was calculated.
The mean corneal thicknesses at the apex point, the center of pupil, the thinnest point, and the mean corneal volume were significantly lower in CT patients than those of controls. The mean intraocular pressure (IOP) was significantly lower in CTs than in controls. There was a significant correlation between BMI and IOP, and BMI was significantly correlated with all pachymetric measurements and corneal volume.
Corneal thicknesses were significantly thinner in CT subjects compared to those in control subjects. The impact of constitutional thinness on corneal parameters should be further investigated.
评估体质消瘦（CT）受试者的角膜参数，并将其与健康个体的参数进行比较。
本观察性横断面研究纳入了24名CT受试者（体重指数<18.5kg/m²）和24名健康受试者（体重指数：18.5 - 25kg/m²）。所有参与者均接受年龄、性别和病史筛查，然后进行详细的眼科检查。通过Scheimpflug成像评估角膜参数。测量所有受试者的身高和体重，并计算体重指数（BMI）。
CT患者的角膜顶点、瞳孔中心、最薄点处的平均角膜厚度以及平均角膜体积均显著低于对照组。CT患者的平均眼压（IOP）显著低于对照组。BMI与IOP之间存在显著相关性，且BMI与所有角膜厚度测量值和角膜体积均显著相关。
与对照组相比，CT受试者的角膜厚度明显更薄。体质消瘦对角膜参数的影响应进一步研究。
