Li Changwei, Liu Tingting, Sun Wenjie, Wu Lang, Zou Zhi-Yong
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, Department of Global Health and Environmental Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, Center for Clinical and Translational Sciences, Mayo Clinic, Rochester, MN, USA and Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China.
Rheumatology (Oxford). 2015 Apr;54(4):697-706. doi: 10.1093/rheumatology/keu391. Epub 2014 Oct 6.
The aims of this study were to estimate the prevalence of arthritis and to identify risk factors of arthritis in a middle-aged and older Chinese adult population.
The China Health and Retirement Longitudinal Study (CHARLS) national survey data were used to estimate overall arthritis prevalence and prevalence by age and gender groups taking into account the complex survey design and response rate. The PROC SURVEYLOGISTIC procedure (SAS 9.3; SAS Institute, Cary, NC, USA) was applied to identify factors associated with arthritis using the CHARLS national survey data. Significant factors were further evaluated in the longitudinal CHARLS pilot study.
The overall prevalence of arthritis among middle-aged and older Chinese adults was 31.4% (95% CI 30.3, 32.4). Prevalence increased with age. Females had a higher prevalence of arthritis than males in each age group. In the cross-sectional analysis, age, gender, education, BMI, sleep duration, vigorous physical activity and self-reported doctor-diagnosed chronic lung disease, hypertension, chronic liver disease, cardiovascular disease, stroke, chronic kidney disease and chronic digestive disease were associated with arthritis. Age, gender, vigorous physical activity and cardiovascular disease were confirmed to be risk factors of arthritis in the longitudinal analysis. Participants with cardiovascular disease were 1.67 times (95% CI 1.02, 2.74) more likely to have self-reported arthritis in a 4-year period of follow-up in the CHARLS pilot study.
Middle-aged and older Chinese adults had a high prevalence of arthritis. Cardiovascular disease is a novel risk factor for arthritis in this population.
本研究旨在估计中国中老年人群中关节炎的患病率，并确定关节炎的危险因素。
利用中国健康与养老追踪调查（CHARLS）的全国调查数据，在考虑复杂调查设计和应答率的情况下，估计总体关节炎患病率以及按年龄和性别分组的患病率。运用PROC SURVEYLOGISTIC程序（SAS 9.3；美国北卡罗来纳州卡里市SAS研究所），通过CHARLS全国调查数据确定与关节炎相关的因素。在CHARLS纵向试点研究中对显著因素进行进一步评估。
中国中老年成年人中关节炎的总体患病率为31.4%（95%置信区间30.3, 32.4）。患病率随年龄增长而上升。在每个年龄组中，女性关节炎患病率均高于男性。在横断面分析中，年龄、性别、教育程度、体重指数、睡眠时间、剧烈体力活动以及自我报告的医生诊断的慢性肺病、高血压、慢性肝病、心血管疾病、中风、慢性肾病和慢性消化系统疾病与关节炎相关。在纵向分析中，年龄、性别、剧烈体力活动和心血管疾病被确认为关节炎的危险因素。在CHARLS试点研究的4年随访期内，患有心血管疾病的参与者自我报告患关节炎的可能性是其他人的1.67倍（95%置信区间1.02, 2.74）。
中国中老年成年人关节炎患病率较高。心血管疾病是该人群患关节炎新的危险因素。
