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腹腔镜胆囊切除术中超声引导下腹部区域阻滞与切口浸润用于术后镇痛的比较研究

Comparative study of ultrasound-guided abdominal field blocks versus port infiltration in laparoscopic cholecystectomies for post-operative pain relief.

作者信息

Saxena Ruchi, Joshi Saurabh, Srivastava Kuldeep, Tiwari Shashank, Sharma Nitin, Valecha Umesh K

机构信息

Department of Anaesthesiology, Dr. B L Kapur Superspeciality Hospital, Rajinder Nagar, New Delhi, India.

Department of Community Medicine, TSM Medical College and Hospital, Lucknow, Uttar Pradesh, India.

出版信息

Indian J Anaesth. 2016 Aug;60(8):578-83. doi: 10.4103/0019-5049.187790.

Abstract

BACKGROUND AND AIMS

Post-operative pain is a major concern for day care surgeries like laparoscopic cholecystectomy. This study aimed to compare the efficacy of ultrasound guided abdominal field blocks (USAFB) with port site infiltrations for post-operative analgesia in terms of quality of pain relief, opioid consumption and patient satisfaction for day care surgeries.

METHODS

Eighty patients presenting for laparoscopic cholecystectomy were randomly allocated to two groups either to receive port-site infiltration of local anaesthetic (n = 40, Group A) or USAFB (n = 40, Group B group). Numeric rating scores (NRS) were measured postoperatively to primarily assess the pain severity and opioid requirements. Data were analysed using Chi-Square test/Fisher's exact test for categorical data and Mann-Whitney test/unpaired t-test for quantitative data.

RESULTS

The study group (Group B) had significantly reduced NRS and opioid consumption over 24 h. The overall fentanyl consumption in patients receiving port infiltrations was approximately twice (200 ΁ 100 μg) as compared to patients in USAFB group (120 ΁ 74 μg) (P < 0.0001). Maximum fentanyl consumption was 400 μg (Group A) and 262 μg (Group B) over 24 h and the minimum requirement was 50 μg and zero, respectively.

CONCLUSION

Superior post-operative analgesia was observed with USAFB which may help in minimising opioid-related adverse effects and facilitating faster recovery.

摘要

背景与目的

术后疼痛是诸如腹腔镜胆囊切除术等日间手术的主要关注点。本研究旨在比较超声引导下腹部区域阻滞(USAFB)与切口局部浸润在日间手术术后镇痛方面的效果,包括疼痛缓解质量、阿片类药物消耗量及患者满意度。

方法

80例行腹腔镜胆囊切除术的患者被随机分为两组,分别接受局部麻醉药切口局部浸润(n = 40,A组)或USAFB(n = 40,B组)。术后测量数字评分量表(NRS)评分,主要评估疼痛严重程度及阿片类药物需求。分类数据采用卡方检验/费舍尔精确检验分析,定量数据采用曼-惠特尼检验/非配对t检验分析。

结果

研究组(B组)24小时内NRS评分及阿片类药物消耗量显著降低。接受切口浸润患者的芬太尼总消耗量(200±100μg)约为USAFB组患者(120±74μg)的两倍(P < 0.0001)。24小时内芬太尼最大消耗量A组为400μg,B组为262μg,最小需求量分别为50μg和0μg。

结论

观察到USAFB术后镇痛效果更佳,这可能有助于将阿片类药物相关不良反应降至最低,并促进更快恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5334/4989809/66cbd06219fe/IJA-60-578-g001.jpg

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