Casey J E, Ferguson G G, Kimura D, Hachinski V C
University Hospital, London, Canada.
J Clin Exp Neuropsychol. 1989 Aug;11(4):461-70. doi: 10.1080/01688638908400906.
Patients who were admitted to hospital for a recent transient ischemic attack were entered into one of three groups based on medical and surgical characteristics; those with an abnormal neurological examination or a focal abnormality on CT Scan were omitted from the study. The two surgical groups (12 patients each) underwent either a left or right endarterectomy for a symptomatic atheroma of the ipsilateral carotid artery. The control group consisted of 12 patients who either demonstrated minor or nonexistent carotid abnormalities or a TIA distribution that was contralateral to what would otherwise have been a surgically treatable lesion. Patients were tested before surgery and again 6-8 weeks later with the WAIS, WMS, and other neuropsychological measures. Significant improvement on some measures at follow-up was strictly equivalent across all groups and was attributed to practice effects.
近期因短暂性脑缺血发作入院的患者，根据医学和手术特征被分为三组；神经系统检查异常或CT扫描有局灶性异常的患者被排除在研究之外。两个手术组（每组12例患者）因同侧颈动脉有症状性动脉粥样硬化分别接受了左或右颈动脉内膜切除术。对照组由12例患者组成，他们要么表现出轻微或不存在的颈动脉异常，要么短暂性脑缺血发作的分布与原本可手术治疗的病变对侧。患者在手术前以及6 - 8周后再次接受韦氏成人智力量表（WAIS）、韦氏记忆量表（WMS）和其他神经心理学测试。随访时在某些测试指标上的显著改善在所有组中完全相同，且归因于练习效应。
