术后认知功能障碍：关注我们对老年人常见术后并发症认识上的差距
Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly.
作者信息
Berger Miles, Nadler Jacob W, Browndyke Jeffrey, Terrando Niccolo, Ponnusamy Vikram, Cohen Harvey Jay, Whitson Heather E, Mathew Joseph P
机构信息
Department of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
Department of Anesthesiology, Duke University Medical Center, Duke South, Orange Zone, Room 4317, Durham, NC 27710, USA.
出版信息
Anesthesiol Clin. 2015 Sep;33(3):517-50. doi: 10.1016/j.anclin.2015.05.008. Epub 2015 Jul 16.
Abstract
Postoperative cognitive dysfunction (POCD) is a common complication associated with significant morbidity and mortality in elderly patients. There is much interest in and controversy about POCD, reflected partly in the increasing number of articles published on POCD recently. Recent work suggests surgery may also be associated with cognitive improvement in some patients, termed postoperative cognitive improvement (POCI). As the number of surgeries performed worldwide approaches 250 million per year, optimizing postoperative cognitive function and preventing/treating POCD are major public health issues. In this article, we review the literature on POCD and POCI, and discuss current research challenges in this area.
摘要
术后认知功能障碍（POCD）是老年患者中一种常见的并发症，与显著的发病率和死亡率相关。人们对POCD有很大的兴趣且存在争议，这在一定程度上反映在最近发表的关于POCD的文章数量不断增加。最近的研究表明，手术在某些患者中也可能与认知改善有关，称为术后认知改善（POCI）。随着全球每年进行的手术数量接近2.5亿例，优化术后认知功能以及预防/治疗POCD是重大的公共卫生问题。在本文中，我们回顾了关于POCD和POCI的文献，并讨论了该领域当前的研究挑战。
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