Schofield Benjamin J, Skarshewski Adam, Lachner Nancy, Ouwerkerk Diane, Klieve Athol V, Dart Peter, Hugenholtz Philip
School of Agriculture and Food Sciences, The University of Queensland, St Lucia, QLD Australia.
Australian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD Australia.
Stand Genomic Sci. 2016 Sep 6;11(1):60. doi: 10.1186/s40793-016-0189-z. eCollection 2016.
Bacillus amyloliquefaciens H57 is a bacterium isolated from lucerne for its ability to prevent feed spoilage. Further interest developed when ruminants fed with H57-inoculated hay showed increased weight gain and nitrogen retention relative to controls, suggesting a probiotic effect. The near complete genome of H57 is ~3.96 Mb comprising 16 contigs. Within the genome there are 3,836 protein coding genes, an estimated sixteen rRNA genes and 69 tRNA genes. H57 has the potential to synthesise four different lipopeptides and four polyketide compounds, which are known antimicrobials. This antimicrobial capacity may facilitate the observed probiotic effect.
解淀粉芽孢杆菌H57是从紫花苜蓿中分离出的一种细菌，因其具有防止饲料变质的能力。当用接种了H57的干草喂养反刍动物时，相对于对照组，它们的体重增加和氮保留量增加，这引发了更多的关注，表明其具有益生菌效应。H57的近乎完整的基因组约为396万个碱基对，由16个重叠群组成。基因组内有3836个蛋白质编码基因、估计16个rRNA基因和69个tRNA基因。H57有潜力合成四种不同的脂肽和四种聚酮化合物，这些都是已知的抗菌剂。这种抗菌能力可能有助于观察到的益生菌效应。
