Gonzalez-Ronquillo Manuel, Villegas-Estrada Daniela, Robles-Jimenez Lizbeth E, Garcia Herrera Ricardo A, Villegas-Vázquez Vanessa L, Vargas-Bello-Pérez Einar
Facultad de Medicina Veterinaria y Zootecnia, Departamento de Nutrición Animal, Instituto Literario 100, Universidad Autónoma del Estado de México, Toluca 50000, Estado de Mexico, Mexico.
División Académica de Ciencias Agropecuarias, Universidad Juárez Autónoma de Tabasco, Carretera Villahermosa-Teapa, km 25, R/A La Huasteca 2a Sección, Villahermosa 86280, Tabasco, Mexico.
Animals (Basel). 2022 Sep 1;12(17):2269. doi: 10.3390/ani12172269.
This meta-analysis determined the effect of Bacillus spp. on growth performance of growing−finishing pigs and then assessed causes for the heterogeneity of responses detected using meta-regression. A database of 22 articles published from 2000 to 2020 was identified, and 9 articles fitted the selection criteria and were integrated in the final database. Statistical analysis was performed to analyze the effect size for ADG, average daily feed intake (ADFI), and F:G ratio using a standardized means difference (SMD) at a 95% confidence interval. A meta-regression analysis was used to investigate the cause of heterogeneity, using the individual SMD for each study assessment as the outcome and the associated SE as the measure of variance. Dietary Bacillus spp. supplementation had no effect on ADFI (SMD: −0.052, p = 0.138) and numerically increased ADG (SMD: 0.113, p = 0.081) and reduced the F:G ratio SMD: −0.127, p < 0.001). Meta-regression outcomes suggested that the number of animals per group was an essential component promoting heterogeneity in ADG. Overall, the inclusion of Bacillus spp. (median 486 mg/d) in growing−finishing pigs can increase ADG and can decrease the F:G ratio.
本荟萃分析确定了芽孢杆菌属对生长育肥猪生长性能的影响，然后使用元回归评估检测到的反应异质性的原因。确定了一个包含2000年至2020年发表的22篇文章的数据库，其中9篇文章符合选择标准并被纳入最终数据库。进行统计分析，以95%置信区间的标准化均值差（SMD）分析平均日增重（ADG）、平均日采食量（ADFI）和料重比（F:G）的效应大小。使用元回归分析来研究异质性的原因，将每项研究评估的个体SMD作为结果，将相关标准误作为方差度量。日粮中添加芽孢杆菌属对ADFI没有影响（SMD：−0.052，p = 0.138），但在数值上增加了ADG（SMD：0.113，p = 0.081）并降低了料重比（SMD：−0.127，p < 0.001）。元回归结果表明，每组动物数量是促进ADG异质性的一个重要因素。总体而言，在生长育肥猪日粮中添加芽孢杆菌属（中位数486毫克/天）可增加ADG并降低料重比。
