Kumar Vinod, Chandra Parijat, Kumar Atul
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Indian J Ophthalmol. 2016 Jul;64(7):504-7. doi: 10.4103/0301-4738.190138.
This study aims to evaluate the use of ultra-wide field (UWF) angiography in patients with Eales disease (ED).
Prospective observational case series in tertiary eye care center.
This study involved 17 patients diagnosed with ED, who underwent UWF fluorescein angiography. The angiograms were analyzed to look for additional information as compared to Early Treatment Diabetic Retinopathy Study seven standard field. The impact of this information in the management of patients was analyzed.
24 eyes of 17 patients with mean age of 26.3 years were diagnosed with ED and underwent UWF angiography. UWF fluorescein angiography was helpful in the documentation of peripheral retinal changes (in 67% of eyes), exact localization of capillary nonperfusion (CNP) (in 54% of eyes), and in determination of vascular involvement (in 21% of eyes). In 33% of eyes, immediate treatment plan changed because of changes picked up on UWF angiography.
UWF angiography helped in the better documentation, exact quantification, and location of CNP areas and better determination of disease activity. UWF imaging may play an important part in the management of patients with ED.
本研究旨在评估超广角（UWF）血管造影在伊尔斯病（ED）患者中的应用。
在三级眼科护理中心进行的前瞻性观察病例系列研究。
本研究纳入了17例诊断为ED的患者，这些患者接受了UWF荧光素血管造影。与糖尿病视网膜病变早期治疗研究的七个标准视野相比，对血管造影片进行分析以寻找更多信息，并分析该信息对患者管理的影响。
17例平均年龄为26.3岁的患者的24只眼睛被诊断为ED并接受了UWF血管造影。UWF荧光素血管造影有助于记录周边视网膜变化（67%的眼睛）、精确确定无灌注毛细血管（CNP）的位置（54%的眼睛）以及确定血管受累情况（21%的眼睛）。在33%的眼睛中，由于UWF血管造影发现的变化，立即改变了治疗计划。
UWF血管造影有助于更好地记录、精确量化和定位CNP区域，并更好地确定疾病活动度。UWF成像可能在ED患者的管理中发挥重要作用。
