Galenok V A, Krivosheev A B, Dikker V E, Piatin M M
Probl Endokrinol (Mosk). 1989 May-Jun;35(3):39-42.
Blood rheological properties and oxygen metabolism were investigated in 50 patients with type I insulin dependent diabetes mellitus. Metabolic and morphological phases of the blood hyperviscosity syndrome were defined in relation to the nature of hemorheological disturbances. Oxygen metabolic disturbances were of unidirectional type manifesting themselves in a decrease in tissue oxygenation and the development of tissue hypoxia. Such disturbances of rheological properties and oxygen metabolism caused the development and progression of diabetic microangiopathies. Therefore pharmacological correction of hemorheological disturbances is a reserve method of therapy of patients with diabetes mellitus.
对50例I型胰岛素依赖型糖尿病患者的血液流变学特性和氧代谢进行了研究。根据血液流变学紊乱的性质确定了血液高粘滞综合征的代谢和形态学阶段。氧代谢紊乱为单向型,表现为组织氧合减少和组织缺氧的发展。这种流变学特性和氧代谢的紊乱导致了糖尿病微血管病变的发生和发展。因此,血液流变学紊乱的药物纠正治疗是糖尿病患者的一种备用治疗方法。