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蛋白质控制饮食、限制蛋白质饮食与低蛋白饮食在非透析慢性肾脏病患者管理中的应用:澳大利亚单中心经验

Protein-controlled versus restricted protein versus low protein diets in managing patients with non-dialysis chronic kidney disease: a single centre experience in Australia.

作者信息

Chan Maria

机构信息

Department of Nutrition and Dietetics, The St. George Hospital, Gray Street, Kogarah, NSW, 2217, Australia.

Department of Renal Medicine The St. George Hospital, Kogarah, NSW, 2217, Australia.

出版信息

BMC Nephrol. 2016 Sep 13;17(1):129. doi: 10.1186/s12882-016-0341-4.

Abstract

Nutrition has been an important part of medical management in patients with chronic kidney disease for more than a century. Since the 1970s, due to technological advances in renal replacement therapy (RRT) such as dialysis and transplantation, the importance of nutrition intervention in non-dialysis stages has diminished. In addition, it appears that there is a lack of high-level evidence to support the use of diet therapy, in particular the use of low protein diets to slow down disease progression. However, nutrition abnormalities are known to emerge well before dialysis is required and are associated with poor outcomes post-commencing dialysis. To improve clinical outcomes it is prudent to incorporate practice research and quality audits into routine care, as part of the continuous clinical practice improvement process. This article summarises the experience of and current practices in a metropolitan tertiary teaching hospital in Sydney, Australia.

摘要

一个多世纪以来,营养一直是慢性肾脏病患者医疗管理的重要组成部分。自20世纪70年代以来,由于透析和移植等肾脏替代疗法(RRT)的技术进步,营养干预在非透析阶段的重要性有所下降。此外,似乎缺乏高级别证据支持使用饮食疗法,特别是使用低蛋白饮食来减缓疾病进展。然而,已知营养异常在需要透析之前就会出现,并且与开始透析后的不良预后相关。为了改善临床结局,将实践研究和质量审核纳入常规护理是审慎之举,这是持续临床实践改进过程的一部分。本文总结了澳大利亚悉尼一家大都市三级教学医院的经验和当前做法。

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