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15/17 translocation in acute promyelocytic leukaemia.

作者信息

Scheres J M, Hustinx T W, de Vaan G A, Rutten F J

出版信息

Hum Genet. 1978 Jul 12;43(1):115-7. doi: 10.1007/BF00396488.

Abstract

A translocation between a chromosome 15 and a chromosome 17 was found in the bone marrow of a 14-year-old boy who had clinical and laboratory symptoms of acute promyelocytic leukemia (APL). As far as we know, this is the sixth case of APL with 15/17 translocation to be reported in the literature. This observation gives further support to the hypothesis that there is an association between this chromosomal rearrangement and APL.

摘要

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