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一名30岁的甲型流感合并大量咯血的孕妇患者:一种常见病原体的非典型表现。

A 30-year-old pregnant patient with massive haemoptysis and influenza A: Atypical presentation of a common pathogen.

作者信息

Nguyen Philippe, Weber Florence, Mahone Michèle

机构信息

Department of Internal Medicine, Saint-Luc Hospital, Centre Hospitalier de l'Université de Montreal, Canada.

出版信息

Obstet Med. 2013 Dec;6(4):172-4. doi: 10.1177/1753495X13486636. Epub 2013 Jul 11.

DOI:10.1177/1753495X13486636
PMID:27656252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5004319/
Abstract

A 30-year-old woman presented at 19 weeks of gestation with symptoms of sore throat, rhinorrhea and haemoptysis that progressed to massive haemoptysis. Her medical history included asthma and a history of smoking prior to pregnancy. Investigations revealed no obvious cause of bleeding. Right lower lobe lobectomy was performed, given the suspicion of a lesion within the intermediate bronchus. The patient developed adult respiratory distress syndrome around 36 h postoperatively. Polymerase chain reaction testing on bronchoalveolar lavage samples was positive for influenza A. Therapy with oseltamivir was initiated. She was discharged two weeks later. This is a rare case of a severe complication from seasonal interpandemic influenza during pregnancy, which underscores the importance of immunization for pregnant women.

摘要

一名30岁女性在妊娠19周时出现咽痛、流涕和咯血症状,后进展为大量咯血。她的病史包括哮喘以及妊娠前有吸烟史。检查未发现明显的出血原因。鉴于怀疑中间支气管内有病变,遂进行了右下叶肺叶切除术。患者在术后约36小时出现成人呼吸窘迫综合征。支气管肺泡灌洗样本的聚合酶链反应检测显示甲型流感呈阳性。开始使用奥司他韦进行治疗。两周后她出院了。这是一例妊娠期季节性流感大流行间期严重并发症的罕见病例,突出了孕妇免疫接种的重要性。

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本文引用的文献

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Afr Health Sci. 2011 Jun;11(2):163-70.
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Factors associated with death or intensive care unit admission due to pandemic 2009 influenza A (H1N1) infection.与大流行 2009 年甲型 H1N1 流感感染导致死亡或入住重症监护病房相关的因素。
Ann Thorac Med. 2011 Apr;6(2):91-5. doi: 10.4103/1817-1737.78429.
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Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection.2009年甲型H1N1流感大流行病毒感染的临床特征
N Engl J Med. 2010 May 6;362(18):1708-19. doi: 10.1056/NEJMra1000449.
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Novel H1N1 influenza A viral infection complicated by alveolar hemorrhage.新型甲型 H1N1 流感病毒感染合并肺泡出血。
Respir Care. 2010 May;55(5):623-5.
5
Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States.美国孕妇中的 2009 年甲型 H1N1 流感大流行病毒病。
JAMA. 2010 Apr 21;303(15):1517-25. doi: 10.1001/jama.2010.479.
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Severe 2009 H1N1 influenza in pregnant and postpartum women in California.加利福尼亚州孕妇和产后妇女中的严重 2009 H1N1 流感。
N Engl J Med. 2010 Jan 7;362(1):27-35. doi: 10.1056/NEJMoa0910444. Epub 2009 Dec 23.
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Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in China.中国 2009 年甲型 H1N1 流感大流行病毒感染初始病例的临床特征。
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