Suppr超能文献

丙型肝炎的治疗与根除障碍

Hepatitis C Treatment and Barriers to Eradication.

作者信息

Konerman Monica A, Lok Anna S F

机构信息

Department of Internal Medicine, University of Michigan Health System, Division of Gastroenterology and Hepatology, Ann Arbor, Michigan, USA.

出版信息

Clin Transl Gastroenterol. 2016 Sep 22;7(9):e193. doi: 10.1038/ctg.2016.50.

Abstract

Current treatment for chronic hepatitis C (CHC) is highly efficacious, well-tolerated, and of short duration for the majority of patients. Despite the dramatic advances in therapy, there remain several barriers to disease eradication. These include deficiencies in screening, diagnosis, and access to care, and high cost of the direct-acting antiviral medications. In addition, incident cases and reinfection associated with injection drug use contribute to the persistent worldwide disease burden. This article will review the current CHC treatments, and outline the remaining gaps in therapy and barriers to disease eradication.

摘要

目前,慢性丙型肝炎(CHC)的治疗对大多数患者而言疗效显著、耐受性良好且疗程较短。尽管治疗取得了巨大进展,但在根除疾病方面仍存在若干障碍。这些障碍包括筛查、诊断和获得治疗方面的不足,以及直接作用抗病毒药物的高昂成本。此外,与注射吸毒相关的新发病例和再感染加重了全球持续存在的疾病负担。本文将综述目前的CHC治疗方法,并概述治疗中仍存在的差距以及根除疾病的障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0d6/5288596/559d617ed933/ctg201650f1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验