Knöpfel N, Martín-Santiago A, Saus C, Escudero-Góngora M M, Del Pozo L J, Gómez C
Servicio de Dermatología, Hospital Universitari Son Espases, Palma de Mallorca, España.
Servicio de Dermatología, Hospital Universitari Son Espases, Palma de Mallorca, España.
Actas Dermosifiliogr. 2017 Apr;108(3):e21-e26. doi: 10.1016/j.ad.2016.02.020. Epub 2016 Sep 21.
The late development of symmetrical, ascending telangiectasias over an extensive area of the skin with no associated systemic manifestations is a common presentation of generalized essential telangiectasia (GET). It was recently suggested that cutaneous collagenous vasculopathy (CCV) is clinically identical to GET but that the 2 conditions can be distinguished by their distinctive histopathologic findings. We present 2 patients, both women, with multiple telangiectasias and describe the histopathologic findings that led to the diagnoses of GET and CCV. Dermoscopic findings in both cases were similar, except that the older telangiectasias in the patient with CCV were violaceous and distributed in a tortuous, serpentine pattern. During follow-up 12 years for the woman with GET and 42 years for the woman with CCV we saw that in GET the lesions remained stable in appearance whereas in CCV there was progressive darkening and morphological changes eventually resulting in superficial varicose veins.
对称性、进行性发展的广泛皮肤区域的毛细血管扩张,且无相关系统表现,是泛发性特发性毛细血管扩张症(GET)的常见表现。最近有人提出,皮肤胶原性血管病(CCV)在临床上与GET相同,但这两种情况可通过其独特的组织病理学表现加以区分。我们报告2例均为女性的患者,她们有多处毛细血管扩张,并描述了导致GET和CCV诊断的组织病理学表现。两例的皮肤镜表现相似,只是CCV患者较陈旧的毛细血管扩张呈紫色,呈扭曲的蛇形分布。在对GET女性患者随访12年、CCV女性患者随访42年期间,我们发现GET患者的病变外观保持稳定,而CCV患者的病变则逐渐变黑并出现形态学改变,最终导致浅表静脉曲张。