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在理想化照射几何条件下,使用站立和坐姿男性混合计算体模计算的质子束转换系数

Conversion Coefficients for Proton Beams using Standing and Sitting Male Hybrid Computational Phantom Calculated in Idealized Irradiation Geometries.

作者信息

Alves M C, Santos W S, Lee C, Bolch W E, Hunt J G, Júnior A B Carvalho

机构信息

Departamento de Física, Universidade Federal de Sergipe; Campus Prof. José Aloísio de Campos, 49.100-000, São Cristóvão - SE, Brazil.

Instituto de Física, Universidade Federal de Uberlândia (INFIS/UFU), Caixa Postal 593, 38400-902 Uberlândia, MG, Brazil.

出版信息

Radiat Prot Dosimetry. 2017 Jun 1;175(1):75-86. doi: 10.1093/rpd/ncw271.

Abstract

The aim of this study was the calculation of conversion coefficients for absorbed doses per fluence (DT/Φ) using the sitting and standing male hybrid phantom (UFH/NCI) exposure to monoenergetic protons with energy ranging from 2 MeV to 10 GeV. Sex-averaged effective dose per fluence (E/Φ) using the results of DT/Φ for the male and female hybrid phantom in standing and sitting postures were also calculated. Results of E/Φ of UFH/NCI standing phantom were also compared with tabulated effective dose conversion coefficients provided in ICRP publication 116. To develop an exposure scenario implementing the male UFH/NCI phantom in sitting and standing postures was used the radiation transport code MCNPX. Whole-body irradiations were performed using the recommended irradiation geometries by ICRP publication 116 antero-posterior (AP), postero-anterior (PA), right and left lateral, rotational (ROT) and isotropic (ISO). In most organs, the conversion coefficients DT/Φ were similar for both postures. However, relative differences were significant for organs located in the lower abdominal region, such as prostate, testes and urinary bladder, especially in the AP geometry. Results of effective dose conversion coefficients were 18% higher in the standing posture of the UFH/NCI phantom, especially below 100 MeV in AP and PA. In lateral geometry, the conversion coefficients values below 20 MeV were 16% higher in the sitting posture. In ROT geometry, the differences were below 10%, for almost all energies. In ISO geometry, the differences in E/Φ were negligible. The results of E/Φ of UFH/NCI phantom were in general below the results of the conversion coefficients provided in ICRP publication 116.

摘要

本研究的目的是计算使用坐姿和站姿男性混合体模(UFH/NCI)暴露于能量范围为2 MeV至10 GeV的单能质子时的每注量吸收剂量转换系数(DT/Φ)。还利用男性和女性混合体模在站立和坐姿下的DT/Φ结果计算了性别平均每注量有效剂量(E/Φ)。UFH/NCI站立体模的E/Φ结果也与ICRP第116号出版物中列出的有效剂量转换系数进行了比较。为了制定一个实施坐姿和站姿男性UFH/NCI体模的照射方案,使用了辐射传输代码MCNPX。全身照射采用ICRP第116号出版物推荐的照射几何条件进行,即前后位(AP)、后前位(PA)、左右侧位、旋转位(ROT)和各向同性位(ISO)。在大多数器官中,两种姿势下的转换系数DT/Φ相似。然而,位于下腹部区域的器官,如前列腺、睾丸和膀胱,相对差异显著,尤其是在AP几何条件下。UFH/NCI体模站立姿势下的有效剂量转换系数结果高18%,尤其是在AP和PA条件下能量低于100 MeV时。在侧位几何条件下,坐姿下20 MeV以下的转换系数值高16%。在ROT几何条件下,几乎所有能量下的差异都低于10%。在ISO几何条件下,E/Φ的差异可以忽略不计。UFH/NCI体模的E/Φ结果总体上低于ICRP第116号出版物中提供的转换系数结果。

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