Gershon E S
Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, MD 20892.
Eur Arch Psychiatry Neurol Sci. 1989;238(5-6):247-50. doi: 10.1007/BF00449805.
Identification of single-gene forms of manic-depressive illness, through linkage demonstrations in pedigrees, offers important opportunities for identification of pathophysiological mechanisms, and for genetic counseling in families with a valid marker of vulnerability.
通过系谱连锁分析来识别躁郁症的单基因形式,为确定病理生理机制以及为有易感性有效标志物的家庭提供遗传咨询提供了重要机会。