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通过增强对红斑毛细血管扩张型玫瑰痤疮临床特征的辨别来改善激光和/或局部治疗。

Improving Treatment of Erythematotelangiectatic Rosacea with Laser and/or Topical Therapy Through Enhanced Discrimination of its Clinical Features.

作者信息

Micali Giuseppe, Gerber Peter Arne, Lacarrubba Francesco, Schäfer Gregor

机构信息

Dermatology Clinic, University of Catania, Italy;

Department of Dermatology, Medical Faculty, University of Düsseldorf, Germany;

出版信息

J Clin Aesthet Dermatol. 2016 Jul;9(7):30-9. Epub 2016 Jul 1.

Abstract

Rosacea is a chronic inflammatory disease that can present with a variety of cutaneous symptoms. Erythematotelangiectatic rosacea is a subtype characterized by flushing (transient erythema), persistent central facial erythema (background erythema), and telangiectasias. The severity of individual symptoms differs in each patient, which can complicate the selection of an appropriate treatment strategy. Evaluation of these specific symptoms has been greatly improved by the routine use of diagnostic tools such as (video) dermatoscopy. Following a thorough clinical assessment, treatment decisions should be made based on the proportion of these individual symptoms in individual patients. Brimonidine 0.33% gel is recommended in the symptomatic treatment of facial erythema, and there is evidence for the efficacy of laser/light-based therapies in the treatment of erythema and telangiectasias. In patients presenting with both marked background erythema and telangiectasias, initial treatment with brimonidine 0.33% gel to target the erythema followed by laser/light-based therapy for the telangiectasias has been shown to be an effective combination in clinical practice. This article aims to facilitate treatment decision-making in clinical practice through: 1) better differentiation of the main symptoms of erythematotelangiectatic rosacea and 2) practical advice for the selection of appropriate treatments, based on clinical case examples.

摘要

酒渣鼻是一种慢性炎症性疾病,可表现出多种皮肤症状。红斑毛细血管扩张型酒渣鼻是一种亚型,其特征为潮红(短暂性红斑)、面部中央持续性红斑(背景红斑)和毛细血管扩张。每位患者的个体症状严重程度各不相同,这可能会使选择合适的治疗策略变得复杂。通过常规使用(视频)皮肤镜等诊断工具,对这些特定症状的评估有了很大改善。在进行全面的临床评估后,应根据个体患者中这些个体症状的比例做出治疗决策。0.33%溴莫尼定凝胶被推荐用于面部红斑的对症治疗,并且有证据表明基于激光/光的疗法在治疗红斑和毛细血管扩张方面有效。在同时出现明显背景红斑和毛细血管扩张的患者中,临床实践表明,先用0.33%溴莫尼定凝胶治疗红斑,然后用基于激光/光的疗法治疗毛细血管扩张是一种有效的联合治疗方法。本文旨在通过以下方式促进临床实践中的治疗决策:1)更好地区分红斑毛细血管扩张型酒渣鼻的主要症状;2)基于临床病例实例,提供选择合适治疗方法的实用建议。

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