• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大剂量静脉注射青霉素G不能阻止莱姆病早期神经表现的进一步发展。

High-dose intravenous penicillin G does not prevent further progression in early neurological manifestation of Lyme borreliosis.

作者信息

Kohler J, Schneider H, Vogt A

机构信息

Neurologische Universitätsklinik und Poliklinik, Freiburg.

出版信息

Infection. 1989 Jul-Aug;17(4):216-7. doi: 10.1007/BF01639522.

DOI:10.1007/BF01639522
PMID:2767763
Abstract

We report two cases of Lyme borreliosis (LB) with erythema migrans (EM) and simultaneous meningopolyneuritis with radicular pain and lymphocytic pleocytosis in the cerebrospinal fluid (CSF). EM and pain disappeared completely under high-dose penicillin G therapy within few a days. Pathological findings in CSF improved. Nevertheless, during and after therapy, neurological signs of LB developed: cranial nerve palsies as well as paresis of extremity muscles with radicular distribution.

摘要

我们报告了2例莱姆病(LB),伴有游走性红斑(EM),同时出现脑膜多发性神经炎,伴有神经根性疼痛和脑脊液(CSF)淋巴细胞增多。在高剂量青霉素G治疗下,EM和疼痛在几天内完全消失。CSF的病理结果有所改善。然而,在治疗期间及之后,LB的神经体征出现了:颅神经麻痹以及神经根分布的肢体肌肉麻痹。

相似文献

1
High-dose intravenous penicillin G does not prevent further progression in early neurological manifestation of Lyme borreliosis.大剂量静脉注射青霉素G不能阻止莱姆病早期神经表现的进一步发展。
Infection. 1989 Jul-Aug;17(4):216-7. doi: 10.1007/BF01639522.
2
[Multiple erythema migrans and facial nerve paralysis: clinical manifestations of early disseminated Lyme borreliosis].[多发性游走性红斑与面神经麻痹:早期播散性莱姆病的临床表现]
Hautarzt. 2014 Apr;65(4):268-71. doi: 10.1007/s00105-014-2782-7.
3
Treatment of Lyme borreliosis with emphasis on neurological disease.莱姆病的治疗,重点关注神经系统疾病。
Ann N Y Acad Sci. 1988;539:317-23. doi: 10.1111/j.1749-6632.1988.tb31866.x.
4
[Lyme borreliosis--the most frequent cause of acute peripheral facial paralysis in childhood].[莱姆病——儿童急性周围性面瘫最常见的病因]
Monatsschr Kinderheilkd. 1989 Mar;137(3):151-7.
5
[Tick bite meningoradiculitis and other neurological aspects of Lyme disease].[蜱叮咬性脑脊神经根炎及莱姆病的其他神经学方面]
Rev Med Interne. 1987 Sep-Oct;8(4):350-6. doi: 10.1016/s0248-8663(87)80005-x.
6
[A case of cranial polyneuropathy presenting with prominent facial diplegia, elevated serum Borrelia burgdorferi antibody and lymphocytic pleocytosis].一例以显著双侧面瘫、血清伯氏疏螺旋体抗体升高及淋巴细胞增多症为表现的颅多神经病
Rinsho Shinkeigaku. 1990 Jul;30(7):787-9.
7
Peripheral facial palsy in childhood--Lyme borreliosis to be suspected unless proven otherwise.儿童周围性面神经麻痹——除非有其他证明,否则应怀疑莱姆病螺旋体病。
Acta Paediatr Scand. 1990 Dec;79(12):1219-24. doi: 10.1111/j.1651-2227.1990.tb11413.x.
8
Lyme borreliosis and peripheral facial palsy.莱姆病与周围性面神经麻痹。
Wien Klin Wochenschr. 1999 Dec 10;111(22-23):970-5.
9
Papilledema Secondary to Neurologic Lyme Borreliosis: A Meta-Case Series.神经莱姆病性脑压增高症:病例系列研究。
J Neuroophthalmol. 2021 Dec 1;41(4):e498-e508. doi: 10.1097/WNO.0000000000000983.
10
[Current aspects in diagnosis and therapy of pediatric facial paralysis].
HNO. 1994 Oct;42(10):624-8.

引用本文的文献

1
Untreated neuroborreliosis: Bannwarth's syndrome evolving into acute schizophrenia-like psychosis. A case report.
J Neurol. 1992 Mar;239(3):129-31. doi: 10.1007/BF00833910.

本文引用的文献

1
[Pain syndromes in tick-borne neuroborreliosis. Clinical aspects and differential diagnosis.].[蜱传神经型莱姆病的疼痛综合征。临床特征与鉴别诊断。]
Schmerz. 1987 Sep;1(2):107-13. doi: 10.1007/BF02527737.
2
Successful treatment of erythema migrans Afzelius.阿弗泽利厄斯游走性红斑的成功治疗。
Acta Derm Venereol. 1951;31(2):235-43.
3
[Jarisch-Herxheimer reaction in erythema migrans disease].[游走性红斑疾病中的雅里施-赫克斯海默反应]
Hautarzt. 1984 Nov;35(11):588-90.
4
Serological diagnosis of erythema migrans disease and related disorders.游走性红斑疾病及相关病症的血清学诊断
Infection. 1984 Sep-Oct;12(5):331-7. doi: 10.1007/BF01651147.
5
Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin.莱姆病的神经系统异常:大剂量静脉注射青霉素治疗成功
Ann Intern Med. 1983 Dec;99(6):767-72. doi: 10.7326/0003-4819-99-6-767.
6
[Erythema chronicum migrans meningitis - a bacterial infectious disease? (author's transl))].
MMW Munch Med Wochenschr. 1974 Nov 8;116(45):1993-8.
7
Intrathecal production of specific antibodies against Borrelia burgdorferi in patients with lymphocytic meningoradiculitis (Bannwarth's syndrome).淋巴细胞性脑膜炎神经根炎(班沃思综合征)患者鞘内产生抗伯氏疏螺旋体的特异性抗体。
J Infect Dis. 1986 Feb;153(2):304-14. doi: 10.1093/infdis/153.2.304.
8
[Erythema migrans borreliosis in the Federal Republic of Germany. Epidemiology and clinical aspects].[德意志联邦共和国的游走性红斑型莱姆病。流行病学及临床方面]
Dtsch Med Wochenschr. 1985 Nov 22;110(47):1803-7. doi: 10.1055/s-2008-1069091.
9
Diagnosis of spirochetal meningitis by enzyme-linked immunosorbent assay and indirect immunofluorescence assay in serum and cerebrospinal fluid.通过酶联免疫吸附测定法和间接免疫荧光测定法检测血清和脑脊液中的螺旋体性脑膜炎
J Clin Microbiol. 1985 May;21(5):819-25. doi: 10.1128/jcm.21.5.819-825.1985.
10
In vitro and in vivo susceptibility of Borrelia burgdorferi.伯氏疏螺旋体的体外和体内药敏性
Eur J Clin Microbiol. 1987 Aug;6(4):424-6. doi: 10.1007/BF02013102.