Amory John K
Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, Washington.
Fertil Steril. 2016 Nov;106(6):1303-1309. doi: 10.1016/j.fertnstert.2016.08.036. Epub 2016 Sep 24.
Although female contraceptives are very effective at preventing unintended pregnancy, some women can not use them because of health conditions or side-effects, leaving some couples without effective contraceptive options. In addition, many men wish to take active responsibility for family planning. Thus, there is a great need for male contraceptives to prevent unintended pregnancies, of which 80-90 million occur annually. At present, effective male contraceptive options are condoms and vasectomy, which are not ideal for all men. Therefore, efforts are under way to develop novel male contraceptives. This paper briefly reviews the advantages and disadvantages of condoms and vasectomies and then discusses the research directed toward development of novel methods of male contraception.
尽管女性避孕药在预防意外怀孕方面非常有效，但一些女性由于健康状况或副作用而无法使用，这使得一些夫妇没有有效的避孕选择。此外，许多男性希望在计划生育中承担积极责任。因此，非常需要男性避孕药来预防意外怀孕，每年有8000万至9000万例意外怀孕发生。目前，有效的男性避孕方法是避孕套和输精管切除术，但并非对所有男性都理想。因此，正在努力开发新型男性避孕药。本文简要回顾了避孕套和输精管切除术的优缺点，然后讨论了旨在开发新型男性避孕方法的研究。
