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未寻求治疗的年轻成年人的注意力缺陷多动障碍症状:与其他形式冲动性的关系。

ADHD symptoms in non-treatment seeking young adults: relationship with other forms of impulsivity.

作者信息

Chamberlain Samuel R, Ioannidis Konstantinos, Leppink Eric W, Niaz Faiza, Redden Sarah A, Grant Jon E

机构信息

1Department of Psychiatry,University of Cambridge,Cambridge,UK.

3Department of Psychiatry & Behavioral Neuroscience,University of Chicago,Chicago, Illinois,USA.

出版信息

CNS Spectr. 2017 Feb;22(1):22-30. doi: 10.1017/S1092852915000875. Epub 2016 Sep 29.

Abstract

OBJECTIVE

Attention-deficit hyperactivity disorder (ADHD) has been associated with various manifestations of impulsivity in adults, including elevated rates of other impulsive disorders, substance use, questionnaire-based impulsivity scores, and inhibitory dysregulation on neurocognitive tests. The relationship between ADHD and all these other forms of impulsivity has yet to be explored within the context of a single comprehensive study.

METHODS

A total of 423 young adults, who gambled ≥5 times in the preceding year, were recruited using media advertisements and undertook detailed assessment including structured psychiatric interview, questionnaires, and neurocognitive tests. Participants with ADHD symptoms were identified using the Adult ADHD Self-Report Scale Screener (ASRS-V1.1) and were compared to controls using multivariate analysis of variance (MANOVA).

RESULTS

ADHD symptoms were found in 20.3% of the sample, but only 7.3% of these subjects had ever received a formal diagnosis. ADHD symptoms were associated with significantly lower quality of life, lower self-esteem, higher emotional dysregulation, higher impulsivity questionnaire scores, more problematic Internet use, greater occurrence of psychiatric disorders, and impaired stop-signal reaction times. Of these variables, stop-signal reaction times and Barratt attentional impulsiveness were the strongest predictors of group classification.

CONCLUSIONS

ADHD symptoms are common and under-diagnosed in young adults who gamble, and are most strongly linked with certain other types of impulsivity (questionnaire- and cognitive-based measures) and with emotional dysregulation, suggesting that these are each important considerations in understanding the pathophysiology of the disorder, but also potential treatment targets. It is necessary to question whether treatment for adult ADHD could be enhanced by considering self-esteem, emotional reactivity, and impaired inhibitory control as specific treatment targets, in addition to the core diagnostic symptoms of the disorder.

摘要

目的

注意力缺陷多动障碍(ADHD)与成人的各种冲动表现有关,包括其他冲动障碍的高发病率、物质使用、基于问卷的冲动得分以及神经认知测试中的抑制失调。ADHD与所有这些其他形式的冲动之间的关系尚未在单一的综合研究背景下进行探讨。

方法

通过媒体广告招募了总共423名在前一年赌博≥5次的年轻成年人,并进行了详细评估,包括结构化精神科访谈、问卷和神经认知测试。使用成人ADHD自我报告量表筛查工具(ASRS-V1.1)识别有ADHD症状的参与者,并使用多变量方差分析(MANOVA)与对照组进行比较。

结果

在样本中发现20.3%的人有ADHD症状,但这些受试者中只有7.3%曾接受过正式诊断。ADHD症状与显著更低的生活质量、更低的自尊、更高的情绪失调、更高的冲动问卷得分、更多问题性的互联网使用、更频繁的精神障碍发生以及受损的停止信号反应时间有关。在这些变量中,停止信号反应时间和巴拉特注意力冲动性是组分类的最强预测因素。

结论

ADHD症状在赌博的年轻成年人中很常见且诊断不足,并且与某些其他类型的冲动(基于问卷和认知的测量)以及情绪失调联系最为紧密,这表明这些在理解该障碍的病理生理学方面都是重要的考虑因素,同时也是潜在的治疗靶点。除了该障碍的核心诊断症状外,将自尊、情绪反应性和受损的抑制控制作为特定治疗靶点来考虑,是否可以增强成人ADHD的治疗,这是有必要探讨的。

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