对接受肉毒杆菌五价（ABCDE）类毒素的人类受试者血清中针对A、B、E和F型肉毒杆菌毒素的中和抗体的评估。
Evaluation of neutralizing antibodies to type A, B, E, and F botulinum toxins in sera from human recipients of botulinum pentavalent (ABCDE) toxoid.
作者信息
Siegel L S
机构信息
Department of Toxinology, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21701-5011.
出版信息
J Clin Microbiol. 1989 Aug;27(8):1906-8. doi: 10.1128/jcm.27.8.1906-1908.1989.
Abstract
Twenty-five serum specimens from personnel immunized with botulinum pentavalent toxoid (ABCDE) had titers of neutralizing antibodies to type A (5.7 to 51.6 IU/ml), type B (0.75 to 18 IU/ml), and type E (0.61 to 10 IU/ml) botulinum toxins. Titers for one type could not be used to predict titers for another type in individuals receiving the toxoid. Cross-neutralizing antibodies to type F botulinum toxin were not detected (less than 0.0125 IU/ml).
摘要
25份来自接受肉毒杆菌五价类毒素（ABCDE）免疫人员的血清标本，对A型（5.7至51.6 IU/ml）、B型（0.75至18 IU/ml）和E型（0.61至10 IU/ml）肉毒杆菌毒素具有中和抗体滴度。在接受类毒素的个体中，一种类型的滴度不能用于预测另一种类型的滴度。未检测到针对F型肉毒杆菌毒素的交叉中和抗体（低于0.0125 IU/ml）。
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