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一种用于增强自体结构性脂肪移植的简单、可靠且廉价的术中体外扩张系统。

A Simple, Reliable, and Inexpensive Intraoperative External Expansion System for Enhanced Autologous Structural Fat Grafting.

作者信息

Oranges Carlo M, Tremp Mathias, Ling Barbara, Wettstein Reto, Largo René D, Schaefer Dirk J

机构信息

Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, Basel, Switzerland.

出版信息

Arch Plast Surg. 2016 Sep;43(5):466-9. doi: 10.5999/aps.2016.43.5.466. Epub 2016 Sep 21.

Abstract

External volume expansion of the recipient site by suction has been proposed as a way of improving fat graft survival. The objective of this study was to present an innovative and simple intraoperative external expansion system to enhance small-volume autologous fat grafting (40-80 mL) and to discuss its background and its mechanism of action. In this system, expansion is performed using a complete vacuum delivery system known as the Kiwi VAC-6000M with a PalmPump (Clinical Innovations). The recipient site is rapidly expanded intraoperatively 10 times for 30 seconds each with a negative pressure of up to 550 mm Hg before autologous fat injection. During this repetitive stimulation, the tissues become grossly expanded, developing macroscopic swelling that regresses slowly over the course of hours following the cessation of the stimulus. The system sets various mechanisms in motion, including scar release, mechanical stimulation, edema, ischemia, and inflammation, which provide an environment conducive for cell proliferation and angiogenesis. In order to maintain the graft construct in its expansive state, all patients are encouraged postoperatively to use the Kiwi three times daily for one minute per session over the course of three days. The handling of this system is simple for both the patients and the surgeon. Satisfactory clinical outcomes have been achieved without significant complications.

摘要

通过抽吸对受区进行体外容积扩张已被提出作为提高脂肪移植存活率的一种方法。本研究的目的是提出一种创新且简单的术中体外扩张系统,以增强小体积自体脂肪移植(40 - 80 mL),并讨论其背景和作用机制。在该系统中,使用一种名为Kiwi VAC - 6000M并配有PalmPump(临床创新公司)的完整真空输送系统进行扩张。在自体脂肪注射前,术中对受区迅速进行10次扩张,每次30秒,负压可达550毫米汞柱。在这种反复刺激过程中,组织会明显扩张,出现肉眼可见的肿胀,在刺激停止后的数小时内缓慢消退。该系统启动了多种机制,包括瘢痕松解、机械刺激、水肿、缺血和炎症,这些机制提供了有利于细胞增殖和血管生成的环境。为了使移植结构保持在扩张状态,鼓励所有患者在术后三天内每天使用Kiwi三次,每次一分钟。该系统对于患者和外科医生来说操作都很简单。已取得了满意的临床效果,且无明显并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5655/5040851/ed1bc667597c/aps-43-466-g001.jpg

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