Sweeney Mary M, Rass Olga, Johnson Patrick S, Strain Eric C, Berry Meredith S, Vo Hoa T, Fishman Marc J, Munro Cynthia A, Rebok George W, Mintzer Miriam Z, Johnson Matthew W
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine.
Mountain Manor Treatment Center.
Exp Clin Psychopharmacol. 2016 Oct;24(5):390-399. doi: 10.1037/pha0000091.
Individuals with substance use disorders have shown deficits in the ability to implement future intentions, called prospective memory. Deficits in prospective memory and working memory, a critical underlying component of prospective memory, likely contribute to substance use treatment failures. Thus, improvement of prospective memory and working memory in substance use patients is an innovative target for intervention. We sought to develop a feasible and valid prospective memory training program that incorporates working memory training and may serve as a useful adjunct to substance use disorder treatment. We administered a single session of the novel prospective memory and working memory training program to participants (n = 22; 13 men, 9 women) enrolled in outpatient substance use disorder treatment and correlated performance to existing measures of prospective memory and working memory. Generally accurate prospective memory performance in a single session suggests feasibility in a substance use treatment population. However, training difficulty should be increased to avoid ceiling effects across repeated sessions. Consistent with existing literature, we observed superior performance on event-based relative to time-based prospective memory tasks. Performance on the prospective memory and working memory training components correlated with validated assessments of prospective memory and working memory, respectively. Correlations between novel memory training program performance and established measures suggest that our training engages appropriate cognitive processes. Further, differential event- and time-based prospective memory task performance suggests internal validity of our training. These data support the development of this intervention as an adjunctive therapy for substance use disorders. (PsycINFO Database Record
患有物质使用障碍的个体在执行未来意图（即前瞻性记忆）的能力方面存在缺陷。前瞻性记忆和工作记忆（前瞻性记忆的一个关键潜在组成部分）的缺陷可能导致物质使用治疗失败。因此，改善物质使用患者的前瞻性记忆和工作记忆是一个创新的干预目标。我们试图开发一种可行且有效的前瞻性记忆训练计划，该计划纳入工作记忆训练，并可作为物质使用障碍治疗的有用辅助手段。我们对参加门诊物质使用障碍治疗的参与者（n = 22；13名男性，9名女性）进行了单次新颖的前瞻性记忆和工作记忆训练计划，并将其表现与前瞻性记忆和工作记忆的现有测量方法进行关联。单次训练中总体准确的前瞻性记忆表现表明在物质使用治疗人群中具有可行性。然而，应增加训练难度以避免在重复训练中出现天花板效应。与现有文献一致，我们观察到在基于事件的前瞻性记忆任务上相对于基于时间的前瞻性记忆任务表现更优。前瞻性记忆和工作记忆训练组件的表现分别与前瞻性记忆和工作记忆的有效评估相关。新颖记忆训练计划表现与既定测量方法之间的相关性表明我们的训练涉及适当的认知过程。此外，基于事件和基于时间的前瞻性记忆任务表现的差异表明我们训练的内部有效性。这些数据支持将这种干预开发为物质使用障碍的辅助治疗方法。（PsycINFO数据库记录
