Han Fubo, Lee Ik-Soo
a College of Pharmacy and Research Institute of Drug Development , Chonnam National University , Gwangju , Republic of Korea.
Nat Prod Res. 2017 Feb;31(3):320-325. doi: 10.1080/14786419.2016.1239092. Epub 2016 Oct 3.
A new prenylated flavonol glycoside (1) was isolated from a 95% methanol extract of the dried and powdered aerial parts of Epimedium koreanum Nakai (Herba Epimedii), along with seven previously known flavonoids (2-8). The chemical structure of the new compound (1) was established to be 5-hydroxy-4'-methoxy-8-(2-hydroxy-3-methyl-3-butenyl)flavone 3-O-α-l-rhamnopyranosyl-7-O-β-D-gluco pyranoside on the basis of spectroscopic methods. The antioxidant activities of these compounds were determined by the DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging assay and kaempferitrin (8) showed a high reactivity with DPPH.
从朝鲜淫羊藿（仙灵脾）干燥粉末状地上部分的95%甲醇提取物中分离出一种新的异戊烯基黄酮醇苷（1），以及七种先前已知的黄酮类化合物（2 - 8）。基于光谱方法确定新化合物（1）的化学结构为5 - 羟基 - 4'- 甲氧基 - 8 -（2 - 羟基 - 3 - 甲基 - 3 - 丁烯基）黄酮3 - O - α - L - 鼠李吡喃糖基 - 7 - O - β - D - 葡萄糖吡喃糖苷。通过DPPH（2,2 - 二苯基 - 1 - 苦基肼）自由基清除试验测定了这些化合物的抗氧化活性，山柰酚苷（8）对DPPH表现出高反应活性。
