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老年患者社区获得性肺炎的临床管理

Clinical management of community acquired pneumonia in the elderly patient.

作者信息

Cilloniz Catia, Ceccato Adrian, San Jose Alicia, Torres Antoni

机构信息

a Department of Pneumology , Institut Clinic del Tórax, Hospital Clinic of Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona (UB) - SGR 911- Ciber de Enfermedades Respiratorias (Ciberes) , Barcelona , Spain.

b Seccion Neumología , Hospital Nacional Alejandro Posadas, Palomar , Buenos Aires , Argentina.

出版信息

Expert Rev Respir Med. 2016 Nov;10(11):1211-1220. doi: 10.1080/17476348.2016.1240037. Epub 2016 Oct 6.

DOI:10.1080/17476348.2016.1240037
PMID:27690702
Abstract

Community acquired pneumonia (CAP) is a major health problem in elderly persons and is associated with high morbidity and mortality. Areas covered: This article reviews the most recent publications relative to CAP in the elderly population, with a focus on epidemiology, prognostic factors, microbial etiology, therapy and prevention. The data discussed in this review were mainly obtained from a non-systematic review using Medline, and references from relevant articles. Expert commentary: CAP can occur at any age, but its incidence and risk of death are linked to increasing age. Age-related changes in the immune system make this population more vulnerable to CAP. Mortality in hospitalized patients with CAP ranges from 10% to 12%. However, in the case of elderly patients, several studies have reported mortality rates of up to 25%. Pneumococcal and influenza vaccination comprise one of the most important preventive approaches for CAP in the elderly.

摘要

社区获得性肺炎(CAP)是老年人面临的一个主要健康问题,且与高发病率和高死亡率相关。涵盖领域:本文回顾了与老年人群CAP相关的最新出版物,重点关注流行病学、预后因素、微生物病因、治疗和预防。本综述中讨论的数据主要来自使用Medline进行的非系统综述以及相关文章的参考文献。专家评论:CAP可发生于任何年龄,但发病率和死亡风险与年龄增长相关。免疫系统的年龄相关变化使该人群更容易患CAP。住院CAP患者的死亡率在10%至12%之间。然而,对于老年患者,多项研究报告死亡率高达25%。肺炎球菌和流感疫苗接种是老年人群预防CAP最重要的方法之一。

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