Heinl Robert E, Dhindsa Devinder S, Mahlof Elliot N, Schultz William M, Ricketts Johnathan C, Varghese Tina, Esmaeeli Amirhossein, Allard-Ratick Marc P, Millard Anthony J, Kelli Heval M, Sandesara Pratik B, Eapen Danny J, Sperling Laurence
Division of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Division of Cardiology, Department of Medicine, Emory University, Atlanta, Georgia, USA.
Can J Cardiol. 2016 Oct;32(10 Suppl 2):S349-S357. doi: 10.1016/j.cjca.2016.07.507. Epub 2016 Jul 22.
The epidemic of obesity has contributed to a growing burden of metabolic syndrome (MetS) and diabetes mellitus (DM) worldwide. MetS is defined as central obesity along with associated factors such as hypertriglyceridemia, low high-density lipoprotein cholesterol, hyperglycemia, and hypertension. MetS and DM are associated with significant cardiovascular morbidity and mortality. Healthy behavioural modification is the cornerstone for reducing the atherosclerotic cardiovascular disease burden in this population. Comprehensive, multidisciplinary cardiac rehabilitation (CR) programs reduce mortality and hospitalizations in patients with MetS and DM. Despite this benefit, patients with MetS and DM are less likely to attend and complete CR because of numerous barriers. Implementation of innovative CR delivery models might improve utilization of CR and cardiovascular outcomes in this high-risk population.
肥胖流行已导致全球代谢综合征（MetS）和糖尿病（DM）负担不断加重。MetS被定义为中心性肥胖以及伴有高甘油三酯血症、低高密度脂蛋白胆固醇、高血糖和高血压等相关因素。MetS和DM与显著的心血管发病率和死亡率相关。健康行为改变是减轻该人群动脉粥样硬化性心血管疾病负担的基石。综合、多学科的心脏康复（CR）项目可降低MetS和DM患者的死亡率及住院率。尽管有此益处，但由于诸多障碍，MetS和DM患者参加并完成CR的可能性较小。实施创新的CR提供模式可能会提高该高危人群对CR的利用率及改善心血管结局。
