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同种异体脾细胞免疫对小鼠存活新生仔鼠数量的影响。

Influence of immunization with allogeneic spleen cells on the number of viable neonates in mice.

作者信息

Heine O, Neppert J, Mueller-Eckhardt G

机构信息

Department of Gynecology and Obstetrics, Justus Liebig-University, Giessen, F.R.G.

出版信息

J Reprod Immunol. 1989 May;15(2):169-73. doi: 10.1016/0165-0378(89)90036-3.

Abstract

Female CBA/J (H-2k) mice mated with male DBA/2J (H-2d) mice show a high level of fetal resorption, which can be reduced by immunization with BALB/c (H-2d) spleen cells. The morphologically defined fetal resorption rate upon which evaluation of the outcome of pregnancy has previously been based in this strain combination is not equivalent to the rate of production of viable neonates.

摘要

雌性CBA/J(H-2k)小鼠与雄性DBA/2J(H-2d)小鼠交配时会出现高水平的胚胎吸收,而用BALB/c(H-2d)脾细胞进行免疫可降低这种情况。在该品系组合中,先前用于评估妊娠结局的形态学定义的胚胎吸收率与存活新生儿的出生率并不等同。

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