Chaouat G, Kiger N, Wegmann T G
J Reprod Immunol. 1983 Nov;5(6):389-92. doi: 10.1016/0165-0378(83)90248-6.
We report here that the high rate of spontaneous resorption observed in CBA/J female mice mated with DBA/2 J males can be dramatically reduced by vaccination with Balb/c male spleen cells, but not by CBA/J or DBA/2 J male spleen cells. This effect correlates with the differential ability of Balb/c spleen cells to induce MLR suppressor activity in CBA/J female mice, and should lead to a better understanding of the immunology of the materno-fetal relationship.
我们在此报告，与DBA/2 J雄性小鼠交配的CBA/J雌性小鼠中观察到的高自发吸收率，可通过用Balb/c雄性脾细胞进行疫苗接种而显著降低，但用CBA/J或DBA/2 J雄性脾细胞则不能。这种效应与Balb/c脾细胞在CBA/J雌性小鼠中诱导混合淋巴细胞反应（MLR）抑制活性的不同能力相关，并且应该有助于更好地理解母胎关系的免疫学。
