Imshenetskiĭ A A, Kirillova N F
Mikrobiologiia. 1978 May-Jun;47(3):403-8.
Acetic acid was found to repress cholinesterase synthesis in the cells of Arthrobacter simplex var. cholinesterasus even at very low concentrations (0.1%). The repression is very stable. It is not eliminated by glucose or an organic acid of the Krebs cycle being added to the medium with acetic acid. The combination of acetic and butyric acids decreases the repression but does not eliminate it. The kinetics of cholinesterase synthesis was different in the cells grown on the medium with acetic acid and the cells cultivated on the medium with acetic acid and glucose, then washed and transferred to a fresh growth medium with glucose and acetylcholine as the sources of carbon.
发现乙酸即使在非常低的浓度（0.1%）下也能抑制简单节杆菌胆碱酯酶变种细胞中的胆碱酯酶合成。这种抑制作用非常稳定。向含有乙酸的培养基中添加葡萄糖或三羧酸循环中的有机酸并不能消除这种抑制作用。乙酸和丁酸的组合可降低抑制作用，但不能消除它。在含有乙酸的培养基上生长的细胞以及在含有乙酸和葡萄糖的培养基上培养、然后洗涤并转移到以葡萄糖和乙酰胆碱作为碳源的新鲜生长培养基上培养的细胞中，胆碱酯酶合成的动力学有所不同。
