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两种相互交织的流行病——肥胖与干扰18岁及以上成年人日常生活的慢性疼痛独立相关;一项基于人群的横断面研究。

Two colliding epidemics - obesity is independently associated with chronic pain interfering with activities of daily living in adults 18 years and over; a cross-sectional, population-based study.

作者信息

Allen Sharon A, Dal Grande Eleonora, Abernethy Amy P, Currow David C

机构信息

Southern Adelaide Palliative Services, Repatriation General Hospital, Daw Park, Adelaide, Australia.

Population Research and Outcomes Studies Unit, Discipline of Medicine, Health Sciences Faculty, Adelaide University, Adelaide, Australia.

出版信息

BMC Public Health. 2016 Sep 30;16(1):1034. doi: 10.1186/s12889-016-3696-3.

DOI:10.1186/s12889-016-3696-3
PMID:27716147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5045593/
Abstract

BACKGROUND

Chronic pain interfering with activities of daily living is highly prevalent in the community. More than 600 million people worldwide are obese. The aim of this paper is to assess if such chronic pain is associated independently with obesity across the adult population, having controlled for other key factors.

METHODS

The South Australian Health Omnibus is an annual, population-based, cross-sectional study. Data on 2616 participants were analysed for episodes of daily pain for three of the preceding six months. Obesity was derived from self-reported height and weight. Multivariable logistic regression analysed the associations between chronic pain interfering with activities of daily living, body mass index (BMI) and key socio-demographic factors.

RESULTS

Chronic pain interfering with activities of daily living peaks in people ≥75 years of age while obesity peaks in the 45-54 age group. Pain and obesity together peak in the 55-74 year age group. In the adjusted multinominal logistic regression model, compared to those with no pain, there was a strong association between obesity and pain that interfered moderately or extremely with day-to-day activities (OR 2.25; 95 % CI 1.57-3.23; p < 0.001) having controlled for respondents' age, gender, rurality, country of birth and highest educational attainment. People over 65 years of age and those with lower educational levels were more likely to experience such chronic pain related to obesity.

CONCLUSION

This study demonstrates a strong association between chronic pain and obesity/morbid obesity in the South Australian population. Prospective, longitudinal data are needed to understand the dynamic interaction between these two prevalent conditions.

摘要

背景

干扰日常生活活动的慢性疼痛在社区中极为普遍。全球有超过6亿人肥胖。本文的目的是在控制其他关键因素的情况下,评估这种慢性疼痛在成年人群中是否与肥胖独立相关。

方法

南澳大利亚综合健康调查是一项基于人群的年度横断面研究。分析了2616名参与者在前六个月中三个月的日常疼痛发作数据。肥胖通过自我报告的身高和体重得出。多变量逻辑回归分析了干扰日常生活活动的慢性疼痛、体重指数(BMI)与关键社会人口学因素之间的关联。

结果

干扰日常生活活动的慢性疼痛在75岁及以上人群中达到峰值,而肥胖在45-54岁年龄组中达到峰值。疼痛和肥胖共同在55-74岁年龄组中达到峰值。在调整后的多项逻辑回归模型中,与无疼痛者相比,肥胖与对日常活动有中度或极度干扰的疼痛之间存在强关联(比值比2.25;95%置信区间1.57-3.23;p<0.001),已控制了受访者的年龄、性别、农村地区、出生国家和最高教育程度。65岁以上人群和教育水平较低者更有可能经历与肥胖相关的这种慢性疼痛。

结论

本研究表明南澳大利亚人群中慢性疼痛与肥胖/病态肥胖之间存在强关联。需要前瞻性纵向数据来了解这两种普遍情况之间的动态相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/5045593/e47017b03507/12889_2016_3696_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/5045593/e47017b03507/12889_2016_3696_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377c/5045593/e47017b03507/12889_2016_3696_Fig1_HTML.jpg

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