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功能性神经障碍的物理治疗。

Physical treatment of functional neurologic disorders.

作者信息

Nielsen G

机构信息

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology and Therapy Services, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

出版信息

Handb Clin Neurol. 2016;139:555-569. doi: 10.1016/B978-0-12-801772-2.00045-X.

Abstract

Physical interventions are widely considered an important part of treatment of functional neurologic disorders (FNDs). The evidence base for physical interventions has been limited to a collection of case series, but the recent publication of several large cohort studies and a randomized controlled trial have provided stronger evidence to support its use. While the evidence for efficacy appears to be promising, details on how this should be delivered remain limited, perhaps due to the dominance of psychologically focused etiologic models. A move towards understanding how the symptoms of FND are generated on a neurobiologic level has resulted in an expansion of pathophysiologic models providing a clearer rationale for physical treatment. In this context, the motor symptoms of FND can be considered as learnt patterns of movement, driven by attention and belief. Physical treatment aims to retrain movement by redirecting attention and addressing unhelpful illness beliefs and behaviors. The patient's problems should be considered in a broad biopsychosocial framework where symptom-predisposing, precipitating, and perpetuating factors can be addressed within a multidisciplinary environment as a gold standard. Further research is required to refine interventions and create evidence-based treatment guidelines.

摘要

物理干预被广泛认为是功能性神经障碍(FNDs)治疗的重要组成部分。物理干预的证据基础一直局限于一系列病例系列研究,但最近发表的几项大型队列研究和一项随机对照试验提供了更强有力的证据来支持其应用。虽然疗效证据似乎很有前景,但关于如何实施物理干预的细节仍然有限,这可能是由于以心理为重点的病因模型占主导地位。朝着理解FND症状如何在神经生物学层面产生的方向发展,导致了病理生理模型的扩展,为物理治疗提供了更清晰的理论依据。在这种情况下,FND的运动症状可被视为由注意力和信念驱动的习得性运动模式。物理治疗旨在通过重新引导注意力以及解决无益的疾病信念和行为来重新训练运动。应在广泛的生物心理社会框架内考虑患者的问题,在多学科环境中作为黄金标准来解决症状易患、促发和持续因素。需要进一步研究以完善干预措施并制定基于证据的治疗指南。

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