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The hyperthermic potentiation of the cytotoxic effect of misonidazole on the EMT6 mouse tumour: relevance of in vitro measurement of in vivo effect.米索硝唑对EMT6小鼠肿瘤细胞毒性作用的热增强:体内效应体外测量的相关性
Br J Cancer Suppl. 1978 Jun;3:173-7.
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In vivo evaluation of the radiosensitizing and cytotoxic properties of newly synthesized electron-affinic drugs.新合成的亲电子药物放射增敏和细胞毒性特性的体内评估。
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The demonstration of in vivo misonidazole tumour toxicity using post radiation hypoxia.利用放疗后缺氧情况对米索硝唑的体内肿瘤毒性进行的论证。
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引用本文的文献

1
Effects of local hyperthermia on the pharmacokinetics of misonidazole in the anaesthetized mouse.局部热疗对麻醉小鼠体内米索硝唑药代动力学的影响。
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Enhancement of hyperthermochemotherapy for human gastric cancer in nude mice by thermosensitization with nitroimidazoles.用硝基咪唑类药物进行热致敏增强裸鼠人胃癌热化学疗法
Br J Cancer. 1988 Jul;58(1):42-5. doi: 10.1038/bjc.1988.158.
3
Intraperitoneal hyperthermic perfusion combined with surgery effective for gastric cancer patients with peritoneal seeding.腹腔热灌注联合手术对伴有腹膜种植的胃癌患者有效。
Ann Surg. 1988 Jul;208(1):36-41. doi: 10.1097/00000658-198807000-00005.
4
Effects on tumour microcirculation in mice of misonidazole and tumour necrosis factor plus hyperthermia.米索硝唑、肿瘤坏死因子联合热疗对小鼠肿瘤微循环的影响。
Br J Cancer. 1992 Jan;65(1):33-6. doi: 10.1038/bjc.1992.6.

本文引用的文献

1
Effect of hyperthermia on differential cytotoxicity of a hypoxic cell radiosensitizer, Ro-07-0582, on mammalian cells in vitro.热疗对缺氧细胞放射增敏剂Ro-07-0582体外对哺乳动物细胞的差异细胞毒性的影响。
Br J Cancer. 1977 Mar;35(3):307-13. doi: 10.1038/bjc.1977.44.
2
Interaction of hyperthermia and the hypoxic cell sensitizer Ro-07-0582 on the EMT6 mouse tumour.热疗与乏氧细胞增敏剂Ro-07-0582对EMT6小鼠肿瘤的相互作用
Br J Cancer. 1977 Mar;35(3):299-306. doi: 10.1038/bjc.1977.43.

米索硝唑对EMT6小鼠肿瘤细胞毒性作用的热增强:体内效应体外测量的相关性

The hyperthermic potentiation of the cytotoxic effect of misonidazole on the EMT6 mouse tumour: relevance of in vitro measurement of in vivo effect.

作者信息

Honess D J, Morgan J E, Bleehen N M

出版信息

Br J Cancer Suppl. 1978 Jun;3:173-7.

PMID:277221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2149428/
Abstract

The effect of local hyperthermia combined with misonidazole and the influence of temperature monitoring on this effect in growth delay studies and in vitro colony assay are described.

摘要

本文描述了在生长延迟研究和体外集落测定中,局部热疗联合米索硝唑的效果以及温度监测对该效果的影响。