School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Renmin St 5625, Changchun, Jilin130022, China.
Nanoscale. 2016 Oct 27;8(42):18027-18031. doi: 10.1039/c6nr05838h.
Although drug delivery based on nanomaterials has shown great potential in practical applications, the trans-membrane mechanism of the drug carrier is still unclear due to technical limitations. Here, we report the dynamic transporting process of a single dendritic polyamidoamine particle via cell membranes in real time by the force tracing technique.
虽然基于纳米材料的药物输送在实际应用中显示出了巨大的潜力，但由于技术限制，药物载体的跨膜机制仍不清楚。在这里，我们通过力追踪技术实时报告了单个树枝状聚酰胺胺颗粒通过细胞膜的动态传输过程。
