Laurito Domenico, Cugnetto Riccardo, Lollobrigida Marco, Guerra Fabrizio, Vestri Annarita, Gianno Francesca, Bosco Sandro, Lamazza Luca, De Biase Alberto
Int J Periodontics Restorative Dent. 2016 Nov/Dec;36(6):877-883. doi: 10.11607/prd.2114.
This study aimed to evaluate the efficacy of an exposed high-density polytetrafluoroethylene (d-PTFE) membrane in preventing epithelial migration in postextraction sockets. For this purpose, a histologic description of the newly formed soft tissue underlying the membrane is presented. The periodontal status of the adjacent teeth was also evaluated to assess the gingival response. Ten premolar extraction sockets were treated. After tooth extraction, the sockets were filled with nanocrystalline hydroxyapatite and covered with d-PTFE membranes. Subperiosteal pockets were created to ensure the stability of the membranes. Membranes were left intentionally exposed and were atraumatically removed after 28 days. At that time, a bioptic specimen of the newly formed soft tissue under the membranes was taken. All the histologic samples showed a dense connective tissue without epithelial cells and no signs of foreign body reaction. No significant variation of the periodontal indices was observed on the teeth adjacent to the extraction sites. The study results indicate that exposed d-PTFE membranes can prevent epithelial migration in healing sockets without consequences on the periodontal health.
本研究旨在评估暴露的高密度聚四氟乙烯（d-PTFE）膜在预防拔牙窝上皮迁移方面的疗效。为此，对膜下方新形成的软组织进行了组织学描述。还评估了相邻牙齿的牙周状况，以评估牙龈反应。对10个前磨牙拔牙窝进行了治疗。拔牙后，拔牙窝用纳米晶羟基磷灰石填充，并用d-PTFE膜覆盖。制作骨膜下袋以确保膜的稳定性。故意让膜暴露在外，并在28天后无创伤地取出。此时，取膜下方新形成的软组织的活检标本。所有组织学样本均显示为致密结缔组织，无上皮细胞，也无异物反应迹象。在拔牙部位相邻的牙齿上未观察到牙周指数有明显变化。研究结果表明，暴露的d-PTFE膜可预防愈合拔牙窝中的上皮迁移，且对牙周健康无影响。
