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使用纳米晶羟基磷灰石(nc-HA)和双层聚四氟乙烯(d-PTFE)膜进行牙槽嵴保存:一项临床、组织学和组织形态计量学研究

Alveolar Ridge Preservation with nc-HA and d-PTFE Membrane: A Clinical, Histologic, and Histomorphometric Study.

作者信息

Laurito Domenica, Lollobrigida Marco, Gianno Francesca, Bosco Sandro, Lamazza Luca, De Biase Alberto

出版信息

Int J Periodontics Restorative Dent. 2017 Mar/Apr;37(2):283-290. doi: 10.11607/prd.2731.

Abstract

Alveolar ridge preservation has become a very common procedure following tooth extraction. This study presents a clinical, histologic, and histomorphometric analysis of postextraction bone changes using nanocrystalline hydroxyapatite (nc-HA) and exposed high-density polytetrafluoroethylene (d-PTFE) membrane. A total of 10 extraction sockets were treated. Clinical measurements were taken after tooth extraction with a customized acrylic stent to ensure the same measurement points. At 6 months, clinical measurements were repeated and bone specimens taken. An overall bone reduction was observed. The histologic and histomorphometric analysis revealed newly formed bone (25.92% ± 18.78%), soft tissue (28.55% ± 9.73%), and residual graft particles (15.43% ± 11.08%). Further studies are necessary to evaluate the efficacy of this technique over the long term.

摘要

牙槽嵴保存已成为拔牙后非常常见的操作。本研究对使用纳米晶羟基磷灰石(nc-HA)和暴露的高密度聚四氟乙烯(d-PTFE)膜的拔牙后骨变化进行了临床、组织学和组织形态计量学分析。共治疗了10个拔牙窝。拔牙后使用定制的丙烯酸支架进行临床测量,以确保测量点相同。6个月时,重复临床测量并采集骨标本。观察到整体骨量减少。组织学和组织形态计量学分析显示新形成的骨(25.92%±18.78%)、软组织(28.55%±9.73%)和残留移植颗粒(15.43%±11.08%)。有必要进行进一步研究以长期评估该技术的疗效。

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