Clark Mathew, Birisci Esma, Anderson Jordan E, Anliker Christina M, Bryant Micheal A, Downs Craig, Dalabih Abdallah
Division of Critical Care Medicine, St. Louis University, St. Louis, MO, USA.
Department of Statistics, University of Missouri, Columbia, MO, USA.
Anesth Essays Res. 2016 Sep-Dec;10(3):607-612. doi: 10.4103/0259-1162.186598.
Current guidelines adopted by the American Academy of Pediatrics calls for prolonged fasting times before performing pediatric procedural sedation and analgesia (PSA). PSA is increasingly provided to children outside of the operating theater by sedation trained pediatric providers and does not require airway manipulation. We investigated the safety of a shorter fasting time compared to a longer and guideline compliant fasting time. We tried to identify the association between fasting time and sedation-related complications.
This is a prospective observational study that included children 2 months to 18 years of age and had an American Society of Anesthesiologists physical status classification of I or II, who underwent deep sedation for elective procedures, performed by pediatric critical care providers. Procedures included radiologic imaging studies, electroencephalograms, auditory brainstem response, echocardiograms, Botox injections, and other minor surgical procedures. Subjects were divided into two groups depending on the length of their fasting time (4-6 h and >6 h). Complication rates were calculated and compared between the three groups.
In the studied group of 2487 subjects, 1007 (40.5%) had fasting time of 4-6 h and the remaining 1480 (59.5%) subjects had fasted for >6 h. There were no statistically significant differences in any of the studied complications between the two groups.
This study found no difference in complication rate in regard to the fasting time among our subjects cohort, which included only healthy children receiving elective procedures performed by sedation trained pediatric critical care providers. This suggests that using shorter fasting time may be safe for procedures performed outside of the operating theater that does not involve high-risk patients or airway manipulation.
美国儿科学会采用的现行指南要求在进行儿科程序性镇静和镇痛(PSA)之前延长禁食时间。经过镇静培训的儿科医护人员越来越多地在手术室之外为儿童提供PSA,且不需要气道操作。我们研究了与较长且符合指南的禁食时间相比,较短禁食时间的安全性。我们试图确定禁食时间与镇静相关并发症之间的关联。
这是一项前瞻性观察性研究,纳入了2个月至18岁、美国麻醉医师协会身体状况分级为I或II级、由儿科重症监护医护人员进行择期手术深度镇静的儿童。手术包括放射影像学检查、脑电图、听觉脑干反应、超声心动图、肉毒杆菌毒素注射及其他小型外科手术。根据禁食时间长短(4 - 6小时和>6小时)将受试者分为两组。计算并比较三组之间的并发症发生率。
在研究的2487名受试者中,1007名(40.5%)禁食时间为4 - 6小时,其余1480名(59.5%)受试者禁食时间>6小时。两组之间在任何研究的并发症方面均无统计学显著差异。
本研究发现,在我们的受试者队列中,禁食时间与并发症发生率之间没有差异,该队列仅包括接受由经过镇静培训的儿科重症监护医护人员进行择期手术的健康儿童。这表明对于在手术室之外进行的、不涉及高危患者或气道操作的手术,采用较短的禁食时间可能是安全的。