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东南欧四个国家部分医院中艰难梭菌PCR核糖体分型的分布及027型和176型的高占比

Distribution of Clostridium difficile PCR ribotypes and high proportion of 027 and 176 in some hospitals in four South Eastern European countries.

作者信息

Rupnik Maja, Tambic Andrasevic Arjana, Trajkovska Dokic Elena, Matas Ivanka, Jovanovic Milica, Pasic Selma, Kocuvan Aleksander, Janezic Sandra

机构信息

National Laboratory for Health, Environment and Food, NLZOH, Maribor, Slovenia; University of Maribor, Faculty of Medicine, Maribor, Slovenia.

Department of Clinical Microbiology, University Hospital for Infectious Diseases, Zagreb, Croatia.

出版信息

Anaerobe. 2016 Dec;42:142-144. doi: 10.1016/j.anaerobe.2016.10.005. Epub 2016 Oct 15.

Abstract

While Clostridium difficile epidemiology is well documented in many European countries, data are largely missing for South Eastern European region. Here we report the PCR ribotype distribution of 249 C. difficile isolates received for typing from six hospital settings from Croatia, Bosnia and Herzegovina, Republic of Macedonia and Serbia in time period from 2008 to 2015. Twenty-four PCR ribotypes were detected. The majority of strains from Bosnia and Herzegovina and Serbia belonged to PCR ribotype 027 (65.8%). Other three dominating PCR ribotypes were 176 (18 strains; Croatia), 001/072 (15 strains; all countries) and 014/020 (15 strains; all countries).

摘要

虽然艰难梭菌的流行病学情况在许多欧洲国家都有详尽记录,但东南欧地区的数据却大多缺失。在此,我们报告了2008年至2015年期间从克罗地亚、波斯尼亚和黑塞哥维那、马其顿共和国以及塞尔维亚的六家医院收集的249株用于分型的艰难梭菌分离株的PCR核糖型分布情况。共检测到24种PCR核糖型。波斯尼亚和黑塞哥维那以及塞尔维亚的大多数菌株属于PCR核糖型027(65.8%)。其他三种主要的PCR核糖型分别是176(18株;克罗地亚)、001/072(15株;所有国家)和014/020(15株;所有国家)。

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