Chong Shu-Ling, Lee Khai Pin, Lee Jan Hau, Ong Gene Yong-Kwang, Ong Marcus Eng Hock
Department of Emergency Medicine, KK Women's and Children's Hospital, Singapore.
Children's Intensive Care Unit, KK Women's and Children's Hospital, Singapore.
Clin Exp Emerg Med. 2015 Mar 31;2(1):1-8. doi: 10.15441/ceem.14.055. eCollection 2015 Mar.
The prompt diagnosis and initial management of pediatric traumatic brain injury poses many challenges to the emergency department (ED) physician. In this review, we aim to appraise the literature on specific management issues faced in the ED, specifically: indications for neuroimaging, choice of sedatives, applicability of hyperventilation, utility of hyperosmolar agents, prophylactic anti-epileptics, and effect of hypothermia in traumatic brain injury. A comprehensive literature search of PubMed and Embase was performed in each specific area of focus corresponding to the relevant questions. The majority of the head injured patients presenting to the ED are mild and can be observed. Clinical prediction rules assist the ED physician in deciding if neuroimaging is warranted. In cases of major head injury, prompt airway control and careful use of sedation are necessary to minimize the chance of hypoxia, while avoiding hyperventilation. Hyperosmolar agents should be started in these cases and normothermia maintained. The majority of the evidence is derived from adult studies, and most treatment modalities are still controversial. Recent multicenter trials have highlighted the need to establish common platforms for further collaboration.
小儿创伤性脑损伤的快速诊断和初始处理给急诊科医生带来了诸多挑战。在本综述中,我们旨在评估有关急诊科面临的特定处理问题的文献,具体包括:神经影像学检查的指征、镇静剂的选择、过度通气的适用性、高渗药物的效用、预防性抗癫痫药物以及低温对创伤性脑损伤的影响。针对与相关问题对应的每个特定重点领域,我们对PubMed和Embase进行了全面的文献检索。大多数到急诊科就诊的头部受伤患者为轻度损伤,可进行观察。临床预测规则有助于急诊科医生决定是否有必要进行神经影像学检查。在严重头部损伤的情况下,迅速控制气道并谨慎使用镇静剂对于将缺氧风险降至最低至关重要,同时要避免过度通气。在这些情况下应开始使用高渗药物并维持正常体温。大多数证据来自成人研究,并且大多数治疗方式仍存在争议。最近的多中心试验强调了建立进一步合作的共同平台的必要性。