Ruan Xiangyan, Cui Yamei, Du Juan, Jin Fengyu, Mueck Alfred Otto
a Department of Gynecological Endocrinology , Beijing Obstetrics & Gynecology Hospital, Capital Medical University , Chaoyang District , Beijing , China.
b Section of Endocrinology and Menopause , University Women's Hospital of Tuebingen, Department of Women's Health, University of Tueiben , Germany.
J Psychosom Obstet Gynaecol. 2017 Sep;38(3):161-169. doi: 10.1080/0167482X.2016.1244181. Epub 2016 Oct 21.
The climacteric symptoms during peri- and postmenopause have not been extensively studied in China. To further understanding of the characteristics of Chinese women during their menopausal transition, the aim of the study was to compare the prevalence and severity of climacteric symptoms of peri- and postmenopausal Chinese women.
The retrospective descriptive study was carried out in perimenopausal and postmenopausal women from 20 provinces of China who visited Beijing Obstetrics & Gynecology hospital during 2008-2015. A total of 1225 women aged 34-76 years without hormone replacement therapy were analyzed. Menopausal status was defined by the "2011 Stages of Reproductive Aging Workshop criteria". The following climacteric symptoms were assessed: fatigue, insomnia, irritability, depression, palpitations, muscle and joint pain, dizziness, vaginal dryness, headache, urinary incontinence, hot flash, sweat, pain during intercourse, and formication.
The most frequent five symptoms were fatigue (75.84%), insomnia (69.39%), irritability (67.02%), palpitations (62.78%), and depression (61.88%). The prevalence of 14 symptoms was significantly higher in the postmenopause compared with the perimenopause status group (all p < .05).The severity of fatigue, insomnia, irritability, palpitation, vaginal dryness, muscle, and joint pain and pain during intercourse was significantly different between the perimenopausal and postmenopausal groups.
The most frequent five symptoms among the investigated 1225 Chinese women were fatigue, insomnia, irritability, palpitations, depression, nearly the same in perimenopausal and postmenopausal women. The prevalence and the severity of most of the symptoms were significantly different between the two groups.
中国对围绝经期和绝经后期的更年期症状尚未进行广泛研究。为了进一步了解中国女性绝经过渡期间的特征,本研究旨在比较中国围绝经期和绝经后期女性更年期症状的患病率及严重程度。
本回顾性描述性研究对2008年至2015年间前往北京妇产医院就诊的来自中国20个省份的围绝经期和绝经后期女性进行。共分析了1225名年龄在34至76岁且未接受激素替代治疗的女性。绝经状态根据“2011年生殖衰老研讨会分期标准”定义。评估了以下更年期症状:疲劳、失眠、易怒、抑郁、心悸、肌肉和关节疼痛、头晕、阴道干燥、头痛、尿失禁、潮热、出汗、性交疼痛和蚁走感。
最常见的五种症状为疲劳(75.84%)、失眠(69.39%)、易怒(67.02%)、心悸(62.78%)和抑郁(61.88%)。与围绝经期状态组相比,14种症状在绝经后期的患病率显著更高(均p < 0.05)。围绝经期和绝经后期组在疲劳、失眠、易怒、心悸、阴道干燥、肌肉和关节疼痛以及性交疼痛的严重程度上存在显著差异。
在被调查的1225名中国女性中,最常见的五种症状为疲劳、失眠、易怒、心悸、抑郁,围绝经期和绝经后期女性的情况大致相同。两组之间大多数症状的患病率和严重程度存在显著差异。