Panteleimonitis Sofoklis, Ahmed Jamil, Ramachandra Meghana, Farooq Muhammad, Harper Mick, Parvaiz Amjad
Department of Minimally Invasive Colorectal Unit, Queen Alexandra Hospital NHS Trust, Portsmouth, UK.
School of Health Sciences and Social Work, University of Portsmouth, Portsmouth, UK.
Int J Colorectal Dis. 2017 Feb;32(2):241-248. doi: 10.1007/s00384-016-2682-7. Epub 2016 Oct 21.
Urological and sexual dysfunction are recognised risks of rectal cancer surgery; however, there is limited evidence regarding urogenital function comparing robotic to laparoscopic techniques. The aim of this study was to assess the urogenital functional outcomes of patients undergoing laparoscopic and robotic rectal cancer surgery.
Urological and sexual functions were assessed using gender-specific validated standardised questionnaires. Questionnaires were sent a minimum of 6 months after surgery, and patients were asked to report their urogenital function pre- and post-operatively, allowing changes in urogenital function to be identified. Questionnaires were sent to 158 patients (89 laparoscopy, 69 robotic) of whom 126 (80 %) responded. Seventy-eight (49 male, 29 female) of the responders underwent laparoscopic and 48 (35 male, 13 female) robotic surgery.
Male patients in the robotic group deteriorated less across all components of sexual function and in five components of urological function. Composite male urological and sexual function score changes from baseline were better in the robotic cohort (p < 0.001). In females, there was no difference between the two groups in any of the components of urological or sexual function. However, composite female urological function score change from baseline was better in the robotic group (p = 0.003).
Robotic rectal cancer surgery might offer better post-operative urological and sexual outcomes compared to laparoscopic surgery in male patients and better urological outcomes in females. Larger scale, prospective randomised control studies including urodynamic assessment of urogenital function are required to validate these results.
泌尿外科和性功能障碍是直肠癌手术公认的风险;然而,关于机器人手术与腹腔镜手术在泌尿生殖功能方面的比较,证据有限。本研究的目的是评估接受腹腔镜和机器人直肠癌手术患者的泌尿生殖功能结局。
使用针对不同性别的经过验证的标准化问卷评估泌尿和性功能。问卷在术后至少6个月发放,要求患者报告术前和术后的泌尿生殖功能,以便确定泌尿生殖功能的变化。问卷发放给了158名患者(89例行腹腔镜手术,69例行机器人手术),其中126名(80%)作出了回应。78名(49名男性,29名女性)回应者接受了腹腔镜手术,48名(35名男性,13名女性)接受了机器人手术。
机器人手术组的男性患者在性功能的所有组成部分以及泌尿功能的五个组成部分中恶化程度较小。机器人手术队列中男性泌尿和性功能综合评分相对于基线的变化更好(p<0.001)。在女性中,两组在泌尿或性功能的任何组成部分上均无差异。然而,机器人手术组女性泌尿功能综合评分相对于基线的变化更好(p=0.003)。
与腹腔镜手术相比,机器人直肠癌手术可能为男性患者提供更好的术后泌尿和性功能结局,为女性患者提供更好的泌尿功能结局。需要开展更大规模的前瞻性随机对照研究,包括对泌尿生殖功能进行尿动力学评估,以验证这些结果。