Luca Fabrizio, Craigg Danielle K, Senthil Maheswari, Selleck Matthew J, Babcock Blake D, Reeves Mark E, Garberoglio Carlos A
Division of Surgical Oncology, Department of Surgery, Loma Linda University, 11175 Campus Street, 21111, Loma Linda, CA, 92350, USA.
Updates Surg. 2018 Sep;70(3):415-421. doi: 10.1007/s13304-018-0581-x. Epub 2018 Aug 17.
Several studies have reported high rates of urogenital dysfunction after open and laparoscopic surgery for rectal cancer. Robotic surgery has several features that could facilitate identification and preservation of autonomic nerves. This manuscript aims to summarize the literature regarding urogenital function after robotic rectal cancer surgery and focus on technical aspects of nerve-sparing total mesorectal excision. Comprehensive searches were conducted through online databases. Selection criteria included: original articles assessing urinary and sexual function after robotic surgery of males and/or females with standardized questionnaires. A total of 16 articles were included in the review. Seven of the nine cohort studies evaluating male sexual function showed earlier recovery or better outcomes in patients operated with robotic techniques. Two studies did not find any statistically significant difference. Three out of four case series found no difference in sexual function scores measured preoperatively and after 1 year. Female sexual function was assessed in seven studies: two case series show no deterioration of at 1 year. Three comparative studies showed no difference between robotic and laparoscopic groups. Two randomized control trials showed different results in terms of male and female sexual functions with better preservation at 1 year in the robotic group in one and no difference in another. Urinary functions assessed in males and/or females in the 16 studies showed no statistically significant differences at long-term follow-up. At present, there is no evidence of superiority of robotic surgery for performing nerve-sparing rectal cancer surgery.
多项研究报告称,直肠癌开放手术和腹腔镜手术后泌尿生殖功能障碍发生率较高。机器人手术具有多项有助于识别和保留自主神经的特点。本文旨在总结机器人直肠癌手术后泌尿生殖功能的相关文献,并重点关注保留神经的全直肠系膜切除术的技术要点。通过在线数据库进行了全面检索。选择标准包括:使用标准化问卷评估男性和/或女性机器人手术后泌尿和性功能的原始文章。本综述共纳入16篇文章。评估男性性功能的9项队列研究中有7项显示,采用机器人技术手术的患者恢复更早或结局更好。两项研究未发现任何统计学上的显著差异。四项病例系列中有三项未发现术前和术后1年的性功能评分有差异。七项研究评估了女性性功能:两项病例系列显示1年时无恶化。三项比较研究显示机器人组和腹腔镜组之间无差异。两项随机对照试验在男性和女性性功能方面显示出不同结果,其中一项试验中机器人组1年时性功能保留更好,另一项试验中无差异。16项研究中对男性和/或女性泌尿功能的评估显示,长期随访时无统计学上的显著差异。目前,没有证据表明机器人手术在进行保留神经的直肠癌手术方面具有优势。