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真菌微生物组——真菌定植者与其宿主之间的友好对话。

The mycobiome – a friendly cross-talk between fungal colonizers and their host.

作者信息

Bożena Dworecka-Kaszak, Iwona Dąbrowska, Ilona Kaszak

机构信息

Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, ul. Ciszewskiego 8, 02-786 Warsaw, Poland

Department of Small Animal Diseases with Clinic, Faculty of Veterinary Medicine, Warsaw University of Life Sciences - SGGW, ul. Nowoursynowska 159C, 02-776 Warsaw, Poland

出版信息

Ann Parasitol. 2016 Oct 1;62(3):175–184. doi: 10.17420/ap6203.51.

Abstract

The organisms colonizing a living host create together with their host a holobiome. The holobioms are networks of mutualistic interactions between host`s cells and microorganisms communities. The fungi are among these microorganisms and have been also well known to infect human and animals. These organisms are associated with a wide range of diseases as superficial or systemic mycoses. Fungi as colonizers can also modify host physiology and metabolism, energy acquisition, vitamin-cofactor availability, development and function of immune system, and even host behavior. The objective of this review is to familiarize with recent data concerning the role of fungi creating mammalian mycobiome in the maintenance of the host health status

摘要

定殖于活体宿主的生物与其宿主共同构成了一个全生物组。全生物组是宿主细胞与微生物群落之间互利共生相互作用的网络。真菌是这些微生物中的一部分,并且众所周知它们会感染人类和动物。这些生物与多种疾病相关,如浅表或系统性真菌病。作为定殖者的真菌还可以改变宿主的生理和代谢、能量获取、维生素辅因子的可用性、免疫系统的发育和功能,甚至宿主行为。本综述的目的是让大家熟悉有关形成哺乳动物真菌组的真菌在维持宿主健康状态方面作用的最新数据。

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