Atmaca L S
Retinal Department, Faculty of Medicine, Ankara University, Turkey.
Graefes Arch Clin Exp Ophthalmol. 1989;227(4):340-4. doi: 10.1007/BF02169409.
Between 1973 and 1987 we recorded 300 cases of Behçet's disease with fundus changes. Our routine preview of each case included examination with the Goldman three-mirror contact lens, ophthalmoscopy, referral for laboratory tests, color fundus photography and, most importantly, fluorescein angiography. The ophthalmological findings led to the proper diagnosis in 254 (85%) of our cases. Fluorescein angiography revealed incipient fundus changes in 38 eyes of 19 medically diagnosed patients with no visual complaints and normal fundi on ophthalmoscopy. Eighty-six percent of our cases had or developed diverse fundus changes bilaterally. The fundus changes we encountered most frequently were hyperemia of the optic disc, macula edema, retinal edema, vascular sheathing, retinal exudate, and retinal hemorrhage. With the exception of eyes with very poor prognoses, only 184 of the 403 eyes that were followed up for 3-120 months (median 12) experienced new insults in the posterior segment; 40 of these became totally blind while 59 maintained their visual status. Early diagnosis is necessary for proper treatment patients with Behçet's disease. Fluorescein angiography is required for early diagnosis and for monitoring the posterior segment involvement closely. This is the most characteristic and often the most serious consequence of Behçet's disease; it may also the first indicator of the disease.
1973年至1987年间，我们记录了300例患有眼底病变的白塞病病例。我们对每个病例的常规检查包括使用戈德曼三面镜接触镜检查、检眼镜检查、实验室检查转诊、彩色眼底照相，最重要的是荧光素血管造影。眼科检查结果使我们254例（85%）的病例得到了正确诊断。荧光素血管造影显示，19例经医学诊断但无视觉症状且检眼镜检查眼底正常的患者中，有38只眼出现了早期眼底病变。我们86%的病例双侧出现或发生了不同的眼底病变。我们最常遇到的眼底病变是视盘充血、黄斑水肿、视网膜水肿、血管鞘、视网膜渗出和视网膜出血。除预后极差的眼睛外，在随访3至120个月（中位数为12个月）的403只眼中，只有184只眼在后段出现了新的损伤；其中40只眼完全失明，59只眼保持了视力状态。早期诊断对白塞病患者的恰当治疗很有必要。荧光素血管造影对于早期诊断和密切监测后段受累情况是必需的。这是白塞病最具特征性且往往最严重的后果；它也可能是该病的首个指标。
