Cialdini A P, Sahel J A, Jalkh A E, Weiter J J, Zakka K, Albert D M
Eye Research Institute and Retina Associates, Boston, MA 02114.
Graefes Arch Clin Exp Ophthalmol. 1989;227(4):348-54. doi: 10.1007/BF02169411.
A 34-year-old Caucasian woman was diagnosed as having a pigmented iris tumor showing recent growth and satellite lesions. The tumor was associated with pigmentation of the anterior chamber angle and secondary unilateral glaucoma. After local excision, histopathologic studies revealed the plump polyhedral cells typical of melanocytoma. However, the examination of additional sections showed evidence of malignancy. The diagnosis of a melanocytoma that transformed into malignant melanoma was made and later confirmed by electron microscopic studies. Following surgical excision of the tumor, the eye maintained normal intraocular pressure. There was no evidence of recurrence 4 years after surgery.
一名34岁的白种女性被诊断患有色素性虹膜肿瘤，该肿瘤近期生长且伴有卫星病灶。该肿瘤与前房角色素沉着及继发性单侧青光眼有关。局部切除术后，组织病理学研究显示出黑素细胞瘤典型的饱满多面体细胞。然而，对额外切片的检查显示有恶性证据。作出了黑素细胞瘤转变为恶性黑色素瘤的诊断，随后经电子显微镜研究证实。肿瘤手术切除后，患眼眼压维持正常。术后4年无复发迹象。
