Sabouri-Rad Sarvenaz, Sabouri-Rad Sara, Sahebkar Amirhossein, Tayarani-Najaran Zahra
Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Dermatology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Curr Pharm Des. 2017;23(11):1649-1666. doi: 10.2174/1381612822666161021152322.
Ginseng has gained fame as one of the most popular herbs originating from Eastern countries. Among different species which are known as ginseng, Panax ginseng C. A. Mey. (Korean or Asian ginseng) is the most frequently used one. Ginsenosides have been proposed to account for most of the biological activities of ginseng. The widely appreciated health-promoting effect of ginseng pertains to the beneficial effects of this plant against immune, cardiovascular and sexual diseases and cancer. In addition, there are some new aspects of the pharmacological activity of this plant which justify its use in dermatologic diseases. In dermatology, ginseng has been investigated mechanistically for its therapeutic effects in photoaging, wound and injury, skin cancer, dermatitis, hair loss, alopecia and cold hypersensitivity. Here, we reviewed experimental and clinical studies exploring the therapeutic efficacy of ginseng and ginsenosides in the field of dermatology.
人参作为源自东方国家最受欢迎的草药之一而声名远扬。在被称为人参的不同种类中，人参（朝鲜或亚洲人参）是最常用的一种。人参皂苷被认为是人参大部分生物活性的原因。人参广受赞誉的促进健康作用与这种植物对免疫、心血管和性疾病以及癌症的有益作用有关。此外，这种植物的药理活性还有一些新的方面，证明其可用于皮肤病。在皮肤病学中，已从机制上研究了人参在光老化、伤口和损伤、皮肤癌、皮炎、脱发、斑秃和寒冷过敏方面的治疗效果。在此，我们综述了探索人参和人参皂苷在皮肤病学领域治疗效果的实验和临床研究。
