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蒙古人种和高加索人种1型糖尿病患者的氧化应激强度

Intensity of Oxidative Stress in Mongoloid and Caucasian Patients with Type 1 Diabetes Mellitus.

作者信息

Kolesnikova L I, Vlasov B Ya, Kolesnikov S I, Darenskaya M A, Grebenkina L A, Semenova N V, Vanteeva O A

机构信息

Research Center of Family Health Problems and Human Reproduction, Irkutsk, Russia.

出版信息

Bull Exp Biol Med. 2016 Oct;161(6):767-769. doi: 10.1007/s10517-016-3505-0. Epub 2016 Oct 26.

DOI:10.1007/s10517-016-3505-0
PMID:27783301
Abstract

Specific features of LPO were studied in Mongoloid and Caucasian patients with type 1 diabetes mellitus. The intensity of LPO in Mongoloid patients was lower than in Caucasians: the level of primary and intermediate products was by lower 1.53 and 1.83 times, while total antioxidant activity was elevated by 1.44 times, which was also supported by oxidative stress coefficient (1.35 in Mongoloids and 2.32 in Caucasians). These differences suggest that differentiated approach is required for the treatment of these patients.

摘要

研究了蒙古人种和高加索人种1型糖尿病患者脂质过氧化(LPO)的具体特征。蒙古人种患者的LPO强度低于高加索人种患者:初级和中间产物水平分别低1.53倍和1.83倍,而总抗氧化活性提高了1.44倍,氧化应激系数也支持这一点(蒙古人种为1.35,高加索人种为2.32)。这些差异表明,对这些患者的治疗需要采用差异化方法。

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