CellNetworks Cluster of Excellence and Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Heidelberg University, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany.
Nat Cell Biol. 2016 Oct 27;18(11):1118-1119. doi: 10.1038/ncb3430.
The endoplasmic reticulum (ER) is the largest membrane-bound organelle in cells, and its size needs to be carefully controlled. Downsizing the ER by autophagy is now shown to involve Sec62, a protein that also helps to build up the organelle. This link suggests a molecular switch for ER size control.
内质网（ER）是细胞中最大的膜结合细胞器，其大小需要仔细控制。现在已经表明，通过自噬使内质网缩小涉及 Sec62，这是一种有助于构建细胞器的蛋白质。这一联系为内质网大小控制提供了一个分子开关。
